The precise construction of chiral molecules is a core research area in chemical science and
technology. Among the plethora of reported synthetic methods, asymmetric catalysis has …

Alkenes and alkynes are feedstock compounds and key units in many natural products,
pharmaceuticals, agrochemicals, and organic functional materials. Hydrofunctionalization …

Conspectus Asymmetric electrophilic reactions provide an ideal method for the construction
of chiral molecules by incorporating one or more functional groups into the parent substrates …

Organoselenium chemistry has become an important tool in synthetic and medicinal
chemistry. Organoselenium reagents are more commonly known as electrophiles, but there …

Abstract The XCF 3 groups (X= O, S, Se) play an increasingly important role in modern
organic chemistry due to their unique electronegativity, lipophilic nature, metabolic stability …

Two types of electrophilic trifluoromethylthiolating reagents were developed in the past 10
years in our laboratory. The development of the first type of reagent …

Due to their unique properties, fluorinated scaffolds are pivotal compounds in
pharmaceuticals, agrochemicals, and materials science. Over the last years, the …

Despite recent advancements in the development of catalytic asymmetric electrophile
induced lactonization reactions of olefinic carboxylic acids, the archetypical …

A photocatalytic approach for the C (sp3)–H trifluoromethylthiolation of amides under mild
reaction conditions is reported. We have developed a protocol that tolerates a large range of …

The trifluoromethylthio (SCF3) functional group has been of increasing importance in drug
design and development as a consequence of its unique electronic properties and high …