Situated between the circulation and the brain, the blood–brain barrier (BBB) protects the
brain from circulating toxins while securing a specialized environment for neuro-glial …

In fura-2-loaded ECV304 cells ionomycin elicited a saturable biphasic change in
intracellular Ca2+ concentration ([Ca2+] i), where the initial phase represented mobilization …

Genetic experiments (loss-of-function and gain-of-function) have established the role of
Angiopoietin/Tie ligand/receptor tyrosine kinase system as a regulator of vessel maturation …

Vascular endothelial cells are ubiquitous for their presence in each and every vessel and
unique for their multifunctional nature. A large number of endothelial functions depend to …

The proliferation and motility of vascular endothelial cells (ECs) are critical steps in
angiogenesis and are strictly controlled by different extracellular signals. Among mitogens …

Stromal interaction molecule (STIM) proteins are putative ER Ca 2+ sensors that recruit and
activate store-operated Ca 2+(SOC) channels at the plasma membrane, a process triggered …

In order to determine the effect of calcium mobilization on mitogen-activated protein (MAP)
kinase activation, we have treated human foreskin fibroblasts (HSWP cells) and human …

The progression through the cell cycle in non‐transformed cells is under the strict control of
extracellular signals called mitogens, that act by eliciting complex cascades of intracellular …

The Drosophila trp (transient receptor potential) gene appears to encode the Drosophila
store-operated channel (SOC), and some mammalian trp homologues have been proposed …

We examined the involvement of tyrosine kinase activity in the bradykinin (BK)-mediated
signal transduction process. Immunoblots with anti-phosphotyrosine antibodies following BK …