Clinical pharmacology of non-steroidal anti-inflammatory drugs: a review

S Bacchi, P Palumbo, A Sponta… - Anti-Inflammatory & …, 2012 - ingentaconnect.com
Non-steroidal anti-inflammatory drugs (NSAIDs) are a group of often chemically unrelated
compounds with some common therapeutic actions and side effects. They have potent anti …

Nitric oxide: what's new to NO?

K Ghimire, HM Altmann, AC Straub… - American Journal of …, 2017 - journals.physiology.org
Nitric oxide (NO) is one of the critical components of the vasculature, regulating key
signaling pathways in health. In macrovessels, NO functions to suppress cell inflammation …

NSAIDs: Old acquaintance in the pipeline for cancer treatment and prevention─ Structural modulation, mechanisms of action, and bright future

S Ramos-Inza, AC Ruberte, C Sanmartin… - Journal of Medicinal …, 2021 - ACS Publications
The limitations of current chemotherapeutic drugs are still a major issue in cancer treatment.
Thus, targeted multimodal therapeutic approaches need to be strategically developed to …

Nonsteroidal anti‐inflammatory therapy: a journey toward safety

C Pereira‐Leite, C Nunes, SK Jamal… - Medicinal research …, 2017 - Wiley Online Library
The efficacy of nonsteroidal anti‐inflammatory drugs (NSAIDs) against inflammation, pain,
and fever has been supporting their worldwide use in the treatment of painful conditions and …

Nonthermal electromagnetic fields: from first messenger to therapeutic applications

AA Pilla - Electromagnetic biology and medicine, 2013 - Taylor & Francis
Nonthermal pulsed electromagnetic fields, from low frequency to pulse-modulated radio
frequency, have been successfully employed as adjunctive therapy for the treatment of …

[图书][B] Electromagnetic fields in biology and medicine

MS Markov - 2015 - books.google.com
Electromagnetic field (EMF) modalities offer an alternative to the increasing use of
pharmaceutical products for therapeutic use. This book presents state-of-the-art EMF use in …

Multiple biological active 4-aminopyrazoles containing trifluoromethyl and their 4-nitroso-precursors: Synthesis and evaluation

YV Burgart, NA Agafonova, EV Shchegolkov… - European Journal of …, 2020 - Elsevier
Nitroso-3-trifluoromethyl-5-alkyl [(het) aryl] pyrazoles were synthesized via one-pot
nitrosation of 1, 3-diketones or their lithium salts followed by treatment of hydrazines …

The evolving landscape for cellular nitric oxide and hydrogen sulfide delivery systems: A new era of customized medications

KM Dillon, RJ Carrazzone, JB Matson… - Biochemical pharmacology, 2020 - Elsevier
Nitric oxide (NO) and hydrogen sulfide (H 2 S) are industrial toxins or pollutants; however,
both are produced endogenously and have important biological roles in most mammalian …

Investigational drugs targeting the prostaglandin E2 signaling pathway for the treatment of inflammatory pain

S Grösch, E Niederberger… - Expert opinion on …, 2017 - Taylor & Francis
Introduction: Non-steroidal anti-inflammatory drugs (NSAID) are the most commonly used
drugs for the treatment of pain, inflammation and fever. Although they are effective for a huge …

Nitric oxide synthase and cyclooxygenase pathways: a complex interplay in cellular signaling

A Sorokin - Current Medicinal Chemistry, 2016 - ingentaconnect.com
The cellular reaction to external challenges is a tightly regulated process consisting of
integrated processes mediated by a variety of signaling molecules, generated as a result of …