Adipogenesis as a potential anti-obesity target: A review of pharmacological treatment and natural products

J Jakab, B Miškić, Š Mikšić, B Juranić… - … syndrome and obesity, 2021 - Taylor & Francis
Obesity is recognized as a severe threat to overall human health and is associated with type
2 diabetes mellitus, dyslipidemia, hypertension, and cardiovascular diseases. Abnormal …

Molecular regulation of adipogenesis and potential anti-adipogenic bioactive molecules

D Moseti, A Regassa, WK Kim - International journal of molecular …, 2016 - mdpi.com
Adipogenesis is the process by which precursor stem cells differentiate into lipid laden
adipocytes. Adipogenesis is regulated by a complex and highly orchestrated gene …

Flavonoids as antiobesity agents: A review

AT Rufino, VM Costa, F Carvalho… - Medicinal Research …, 2021 - Wiley Online Library
Obesity is a global health problem that affects all age groups in both developing and
developed countries. In recent years, the prevalence of overweight and obesity has reached …

Heterogeneity of adipose tissue in development and metabolic function

T Schoettl, IP Fischer, S Ussar - Journal of Experimental …, 2018 - journals.biologists.com
Adipose tissue is a central metabolic organ. Unlike other organs, adipose tissue is
compartmentalized into individual depots and distributed throughout the body. These …

Evidence of flavonoids on disease prevention

M Li, M Qian, Q Jiang, B Tan, Y Yin, X Han - Antioxidants, 2023 - mdpi.com
A growing body of evidence highlights the properties of flavonoids in natural foods for
disease prevention. Due to their antioxidative, anti-inflammatory, and anti-carcinogenic …

Diabetes and plant‐derived natural products: From ethnopharmacological approaches to their potential for modern drug discovery and development

AK Jugran, S Rawat, HP Devkota, ID Bhatt… - Phytotherapy …, 2021 - Wiley Online Library
Diabetes is a disease of serious concern faced by the health care industry today. Primary
diabetes mellitus and its complications are still costly to manage with modern drugs …

Modulation of adipose tissue inflammation by bioactive food compounds

N Siriwardhana, NS Kalupahana, M Cekanova… - The Journal of nutritional …, 2013 - Elsevier
Adipose tissue has an important endocrine function in the regulation of whole-body
metabolism. Obesity leads to a chronic low-grade inflammation of the adipose tissue, which …

Dietary phytochemicals and their potential effects on obesity: a review

M González-Castejón, A Rodriguez-Casado - Pharmacological research, 2011 - Elsevier
The incidence of obesity is rising at an alarming rate and is becoming a major public health
concern with incalculable social costs. Indeed, obesity facilitates the development of …

Current methods of adipogenic differentiation of mesenchymal stem cells

MA Scott, VT Nguyen, B Levi… - Stem cells and …, 2011 - liebertpub.com
There has been a recent increase in our understanding in the isolation, culture, and
differentiation of mesenchymal stem cells (MSCs). Concomitantly, the availability of MSCs …

Genistein: a promising therapeutic agent for obesity and diabetes treatment

N Behloul, G Wu - European journal of pharmacology, 2013 - Elsevier
Obesity and type 2 diabetes are serious public health problems worldwide. Considerable
efforts have highlighted the link between these two diseases. The high levels of pro …