The prevalence and incidence of type 2 diabetes, representing. 90% of all cases of diabetes,
are increasing rapidly throughout the world. The International Diabetes Federation has …

Eur J Clin Invest 2011; 41 (6): 679–692 Abstract Background Recent genome‐wide
association studies enlarged our knowledge about the genetic background of type 2 …

摘要2 型糖尿病已经成为全球公共卫生的主要挑战. 迄今为止, 通过全基因组关联研究(genome‐
wide association studies, GWAS) 总共已经鉴定出了83 个2 型糖尿病易感位点. 为了发现2 …

Background Obesity is associated with vitamin D deficiency, and both are areas of active
public health concern. We explored the causality and direction of the relationship between …

Mendelian randomisation analyses use genetic variants as instrumental variables (IVs) to
estimate causal effects of modifiable risk factors on disease outcomes. Genetic variants …

Background An allele score is a single variable summarizing multiple genetic variants
associated with a risk factor. It is calculated as the total number of risk factor-increasing …

Importance Neonates born to overweight or obese women are larger and at higher risk of
birth complications. Many maternal obesity-related traits are observationally associated with …

Background: The prevalence of type 2 diabetes (DM) in children is disturbingly increasing in
parallel with the increasing childhood obesity. Better knowledge regarding the …

Objectives To assess the performance of a panel of common single nucleotide
polymorphisms (genotypes) associated with type 2 diabetes in distinguishing incident cases …

The advent of genome-wide association studies has accelerated the discovery of novel
genetic markers, in particular single nucleotide polymorphisms (SNPs) that are associated …