Monoallelic expression of olfactory receptors
K Monahan, S Lomvardas - Annual review of cell and …, 2015 - annualreviews.org
The sense of smell collects vital information about the environment by detecting a multitude
of chemical odorants. Breadth and sensitivity are provided by a huge number of …
of chemical odorants. Breadth and sensitivity are provided by a huge number of …
Maturation of the olfactory sensory neuron and its cilia
Olfactory sensory neurons (OSNs) are bipolar neurons, unusual because they turn over
continuously and have a multiciliated dendrite. The extensive changes in gene expression …
continuously and have a multiciliated dendrite. The extensive changes in gene expression …
[HTML][HTML] An epigenetic signature for monoallelic olfactory receptor expression
Constitutive heterochromatin is traditionally viewed as the static form of heterochromatin that
silences pericentromeric and telomeric repeats in a cell cycle-and differentiation …
silences pericentromeric and telomeric repeats in a cell cycle-and differentiation …
[HTML][HTML] An epigenetic trap stabilizes singular olfactory receptor expression
The molecular mechanisms regulating olfactory receptor (OR) expression in the mammalian
nose are not yet understood. Here, we identify the transient expression of histone …
nose are not yet understood. Here, we identify the transient expression of histone …
The human olfactory transcriptome
Background Olfaction is a versatile sensory mechanism for detecting thousands of volatile
odorants. Although molecular basis of odorant signaling is relatively well understood …
odorants. Although molecular basis of odorant signaling is relatively well understood …
Extrasensory perception: odorant and taste receptors beyond the nose and mouth
G protein-coupled receptors (GPCRs) represent the largest family of transmembrane
receptors and are prime therapeutic targets. The odorant and taste receptors account for …
receptors and are prime therapeutic targets. The odorant and taste receptors account for …
Translational potential of olfactory mucosa for the study of neuropsychiatric illness
K Borgmann-Winter, SL Willard, D Sinclair… - Translational …, 2015 - nature.com
The olfactory mucosa (OM) is a unique source of regenerative neural tissue that is readily
obtainable from living human subjects and thus affords opportunities for the study of …
obtainable from living human subjects and thus affords opportunities for the study of …
[图书][B] The neurobiology of olfaction
A Menini - 2009 - taylorfrancis.com
Comprehensive Overview of Advances in OlfactionThe common belief is that human smell
perception is much reduced compared with other mammals, so that whatever abilities are …
perception is much reduced compared with other mammals, so that whatever abilities are …
Combinatorial Activation and Repression by Seven Transcription Factors Specify Drosophila Odorant Receptor Expression
S Jafari, L Alkhori, A Schleiffer, A Brochtrup… - PLoS …, 2012 - journals.plos.org
The mechanism that specifies olfactory sensory neurons to express only one odorant
receptor (OR) from a large repertoire is critical for odor discrimination but poorly understood …
receptor (OR) from a large repertoire is critical for odor discrimination but poorly understood …
[HTML][HTML] Sensational placodes: neurogenesis in the otic and olfactory systems
EC Maier, A Saxena, B Alsina, ME Bronner… - Developmental …, 2014 - Elsevier
For both the intricate morphogenetic layout of the sensory cells in the ear and the elegantly
radial arrangement of the sensory neurons in the nose, numerous signaling molecules and …
radial arrangement of the sensory neurons in the nose, numerous signaling molecules and …