Glioblastoma (GBM) is a highly malignant brain tumor characterized by a heterogeneous
population of genetically unstable and highly infiltrative cells that are resistant to …

Introducing novel strategies, concepts, and technologies that speed up drug discovery and
the drug development cycle is of great importance both in the highly competitive …

Low-passage, serum-free cell lines cultured from patient tumour tissue are the gold-standard
for preclinical studies and cellular investigations of glioblastoma (GBM) biology, yet …

A newly engineered palladacycle that contains substituents on the biphenyl rings along with
the ligand HandaPhos is especially well-matched to an aqueous micellar medium, enabling …

Herein, we describe the first linear-selective hydroarylation reaction of unactivated alkenes
and styrenes with aryl boronic acids, which was achieved by introducing a directing group …

Simple Summary Cancer is among the leading causes of death, and cancer therapy suffers
from many drawbacks, the lack of selectivity being most noteworthy. In this review, we …

Microtubules are key components of the eukaryotic cytoskeleton with essential roles in cell
division, intercellular transport, cell morphology, motility, and signal transduction. They are …

Cells generate a highly diverse microtubule network to carry out different activities. This
network is comprised of distinct tubulin isotypes, tubulins with different post-translational …

Due to the three domains of the colchicine-site which is conducive to the combination with
small molecule compounds, colchicine-site on the tubulin has become a common target for …

Photoresponsive materials afford spatiotemporal control over desirable physical, chemical
and biological properties. For advanced applications, there is need for molecular …