There is an epidemic of opioid use, abuse, and misuse in the United States, which results in
significant morbidity and mortality. It may be difficult to reduce perioperative opioid use given …

Background: The pathophysiology of pain involves complex nervous system interactions
after initial noxious stimuli. When stimuli persist, biochemical and structural changes occur in …

Nerve blocks improve postoperative analgesia, but their benefits may be short-lived. This
quantitative review examines whether perineural dexmedetomidine as a local anaesthetic …

In the past ten years there has been recognition that chronic post-surgical pain is a
significant problem. This is a complex area of research and although the quality of studies …

BACKGROUND: Regional anesthesia (RA) provides excellent anesthesia and analgesia for
many surgical procedures. Anesthesiologists and patients must understand the risks in …

BACKGROUND: Improving perioperative efficiency and throughput has become
increasingly important in the modern practice of anesthesiology. Fast-track surgery …

IMPLICATIONS: This meta-analysis suggests that regional anesthesia offers several
advantages over general anesthesia for ambulatory surgery, such as decreased …

Brachial plexus blockade is the cornerstone of the peripheral nerve regional anesthesia
practice of most anesthesiologists. As part of the American Society of Regional Anesthesia …

Background Rebound pain is a common, yet under-recognised acute increase in pain
severity after a peripheral nerve block (PNB) has receded, typically manifesting within 24 h …

Preventive Analgesia by Local Anesthetics: The Reduction of... : Anesthesia & Analgesia
Preventive Analgesia by Local Anesthetics: The Reduction of Postoperative Pain by Peripheral …