The value of universally available raw NMR data for transparency, reproducibility, and integrity in natural product research

JB McAlpine, SN Chen, A Kutateladze… - Natural product …, 2019 - pubs.rsc.org
Covering: up to 2018 With contributions from the global natural product (NP) research
community, and continuing the Raw Data Initiative, this review collects a comprehensive …

Natural and synthetic 5‐(3′‐indolyl) oxazoles: Biological activity, chemical synthesis and advanced molecules

JR Liu, EY Jiang, O Sukhbaatar… - Medicinal Research …, 2025 - Wiley Online Library
Abstract 5‐(3′‐Indolyl) oxazole moiety is a privileged heterocyclic scaffold, embedded in
many biologically interesting natural products and potential therapeutic agents. Compounds …

Pyrones as bacterial signaling molecules

AO Brachmann, S Brameyer, D Kresovic… - Nature chemical …, 2013 - nature.com
Bacteria communicate via small diffusible molecules and thereby mediate group-
coordinated behavior, a process referred to as quorum sensing. The prototypical quorum …

Indexing the Pseudomonas specialized metabolome enabled the discovery of poaeamide B and the bananamides

DD Nguyen, AV Melnik, N Koyama, X Lu… - Nature …, 2016 - nature.com
Pseudomonads are cosmopolitan microorganisms able to produce a wide array of
specialized metabolites. These molecules allow Pseudomonas to scavenge nutrients, sense …

Alkynyl Thioethers in Gold‐Catalyzed Annulations To Form Oxazoles

RJ Reddy, MP Ball‐Jones… - Angewandte Chemie …, 2017 - Wiley Online Library
Non‐oxidative, regioselective, and convergent access to densely functionalized oxazoles is
realized in a functional‐group tolerant manner using alkynyl thioethers. Sulfur‐terminated …

Promoter Activation in Δhfq Mutants as an Efficient Tool for Specialized Metabolite Production Enabling Direct Bioactivity Testing

E Bode, AK Heinrich, M Hirschmann… - Angewandte …, 2019 - Wiley Online Library
Natural products (NPs) from microorganisms have been important sources for discovering
new therapeutic and chemical entities. While their corresponding biosynthetic gene clusters …

Efficient and Flexible Synthesis of Highly Functionalised 4‐Aminooxazoles by a Gold‐Catalysed Intermolecular Formal [3+ 2] Dipolar Cycloaddition

AD Gillie, R Jannapu Reddy… - Advanced Synthesis & …, 2016 - Wiley Online Library
Oxazoles are important motifs within bioactive and functional materials. Complex, fully
substituted and functionalised 4‐aminooxazoles are accessed by an efficient intermolecular …

Regiodivergent Synthesis of 4‐and 5‐Sulfenyl Oxazoles from Alkynyl Thioethers

P Sekar, A Gupta, LE English… - … A European Journal, 2024 - Wiley Online Library
The regiodivergent synthesis of 4‐and 5‐sulfenyl oxazoles from 1, 4, 2‐dioxazoles and
alkynyl thioethers has been achieved. Gold‐catalysed conditions are used to favour the …

Review on chemistry of oxazole derivatives: Current to future therapeutic prospective

S Joshi, M Mehra, R Singh, S Kakar - Egyptian Journal of Basic …, 2023 - Taylor & Francis
Oxazole and its derivatives play a very essential role in the area of medicinal chemistry.
Oxazole nucleus is heterocyclic five-membered ring that seemed to be investigated in the …

Structure and Biosynthesis of Xenoamicins from Entomopathogenic Xenorhabdus

Q Zhou, F Grundmann, M Kaiser… - … A European Journal, 2013 - Wiley Online Library
During the search for novel natural products from entomopathogenic Xenorhabdus
doucetiae DSM17909 and X. mauleonii DSM17908 novel peptides named xenoamicins …