Photoactivatable (alternatively, photoremovable, photoreleasable, or photocleavable) protecting groups (PPGs), also known as caged or photocaged compounds, are used to …
M Gao, F Yu, C Lv, J Choo, L Chen - Chemical Society Reviews, 2017 - pubs.rsc.org
Surgical resection of solid tumors is currently the gold standard and preferred therapeutic strategy for cancer. Chemotherapy drugs also make a significant contribution by inhibiting …
The folate receptor (FR) is a recognised biomarker for tumour cells due to its overexpression on a large number of tumours. Consequently, the FR has been exploited by many diagnostic …
The ability to gain spatiotemporal information, and in some cases achieve spatiotemporal control, in the context of drug delivery makes theranostic fluorescent probes an attractive …
Stimulus-cleavable nanoscale drug delivery systems are receiving significant attention owing to their capability of achieving exquisite control over drug release via the exposure to …
R Kumar, WS Shin, K Sunwoo, WY Kim… - Chemical Society …, 2015 - pubs.rsc.org
The advances in genomics, proteomics, and bioinformatics have directed the development of new anticancer agents to reduce drug abuse and increase safe and specific drug …
VF Otvagin, NS Kuzmina, ES Kudriashova… - Journal of medicinal …, 2022 - ACS Publications
Photodynamic therapy (PDT) is a treatment modality where light-mediated activation of photosensitizers in a patient's body leads to the generation of cytotoxic reactive oxygen …
MH Lee, A Sharma, MJ Chang, J Lee, S Son… - Chemical Society …, 2018 - pubs.rsc.org
Theranostic systems are receiving ever-increasing attention due to their potential therapeutic utility, imaging enhancement capability, and promise for advancing the field of …
J Liang, B Liu - Bioengineering & translational medicine, 2016 - Wiley Online Library
Reactive oxygen species (ROS) play an important role in signal transduction and metabolism. Over‐produced ROS in cells or tissues, however, often leads to oxidation stress …