Peripheral immune-based biomarkers in cancer immunotherapy: can we realize their predictive potential?

AB Nixon, KA Schalper, I Jacobs, S Potluri… - … for immunotherapy of …, 2019 - Springer
The immunologic landscape of the host and tumor play key roles in determining how
patients will benefit from immunotherapy, and a better understanding of these factors could …

Current and prospective protein biomarkers of lung cancer

TN Zamay, GS Zamay, OS Kolovskaya, RA Zukov… - Cancers, 2017 - mdpi.com
Lung cancer is a malignant lung tumor with various histological variants that arise from
different cell types, such as bronchial epithelium, bronchioles, alveoli, or bronchial mucous …

Aptamer‐functionalized quantum dots as theranostic nanotools against cancer and bacterial infections: a comprehensive overview of recent trends

F Davodabadi, S Mirinejad… - Biotechnology …, 2023 - Wiley Online Library
Aptamers (Apts) are synthetic nucleic acid ligands that can be engineered to target various
molecules, including amino acids, proteins, and pharmaceuticals. Through a series of …

CAR‐T cell therapy for lung cancer: Potential and perspective

L Chen, F Chen, J Li, Y Pu, C Yang, Y Wang… - Thoracic …, 2022 - Wiley Online Library
Lung cancer is the highest incidence and mortality of all cancers around the world. In the
present immunotherapy era, an increasing number of immunotherapeutic agents including …

Post-translational modifications in tumor-associated antigens as a platform for novel immuno-oncology therapies

AK Srivastava, G Guadagnin, P Cappello, F Novelli - Cancers, 2022 - mdpi.com
Simple Summary Tumor-associated antigens (TAAs) are antigens present in tumor cells, but
are also expressed in normal cells. However, TAAs are aberrantly expressed by tumor cells …

Aptasensors as a new sensing technology developed for the detection of MUC1 mucin: A review

M Yousefi, S Dehghani, R Nosrati, H Zare… - Biosensors and …, 2019 - Elsevier
Abstract Mucin 1 protein (MUC1) is a membrane-associated glycoprotein overexpressed in
the majority of human malignancies and considered as a predominant protein biomarker in …

An enzymatic toolkit for selective proteolysis, detection, and visualization of mucin-domain glycoproteins

DJ Shon, SA Malaker, K Pedram… - Proceedings of the …, 2020 - National Acad Sciences
Densely O-glycosylated mucin domains are found in a broad range of cell surface and
secreted proteins, where they play key physiological roles. In addition, alterations in mucin …

Fiber SPR biosensor sensitized by MOFs for MUC1 protein detection

R Wang, C Liu, Y Wei, Z Ran, T Jiang, C Liu, C Shi… - Talanta, 2023 - Elsevier
The concentration of tumor markers is low, which needs a highly sensitive, stable and fast
detection method. In this paper, we proposed and demonstrated a U-shape fiber SPR …

Anti‐MUC1 aptamer: a potential opportunity for cancer treatment

MS Nabavinia, A Gholoobi, F Charbgoo… - Medicinal research …, 2017 - Wiley Online Library
Abstract Mucin 1 (MUC1) is a protein usually found on the apical surface of most normal
secretory epithelial cells. However, in most adenocarcinomas, MUC1 is overexpressed, so …

The role of MUC1 in renal cell carcinoma

M Milella, M Rutigliano, F Lasorsa, M Ferro, R Bianchi… - Biomolecules, 2024 - mdpi.com
Mucins are a family of high-molecular-weight glycoproteins. MUC1 is widely studied for its
role in distinct types of cancers. In many human epithelial malignancies, MUC1 is frequently …