Colchicine—update on mechanisms of action and therapeutic uses

YY Leung, LLY Hui, VB Kraus - Seminars in arthritis and rheumatism, 2015 - Elsevier
Objectives To review the literature and provide an update on the mechanisms of action and
therapeutic uses of oral colchicine in arthritis and inflammatory conditions. Methods We …

Update on colchicine, 2017

A Slobodnick, B Shah, S Krasnokutsky… - …, 2018 - academic.oup.com
Colchicine is an ancient medication that is currently approved for the treatment of gout and
FMF. However, colchicine has a wide range of anti-inflammatory activities, and studies …

Effects of acute colchicine administration prior to percutaneous coronary intervention: COLCHICINE-PCI randomized trial

B Shah, M Pillinger, H Zhong, B Cronstein… - Circulation …, 2020 - Am Heart Assoc
Background: Vascular injury and inflammation during percutaneous coronary intervention
(PCI) are associated with increased risk of post-PCI adverse outcomes. Colchicine …

[图书][B] Textbook of pediatric rheumatology e-book

RE Petty, RM Laxer, CB Lindsley, L Wedderburn… - 2020 - books.google.com
Offering up-to-date, comprehensive coverage of disease progression, diagnosis,
management, and prognosis, Textbook of Pediatric Rheumatology is the definitive reference …

Anakinra for colchicine‐resistant familial Mediterranean fever: a randomized, double‐blind, placebo‐controlled trial

I Ben‐Zvi, O Kukuy, E Giat, E Pras, O Feld… - Arthritis & …, 2017 - Wiley Online Library
Objective Familial Mediterranean fever (FMF) is refractory to colchicine prophylaxis in 10–
20% of patients. In a number of patient series, treatment with anakinra, an interleukin‐1 …

Colchicine update: 2008

RA Terkeltaub - Seminars in arthritis and rheumatism, 2009 - Elsevier
OBJECTIVES: To review recent advances in the understanding of molecular mechanisms of
drug disposition and cellular mechanisms of action and targets of colchicine, and disease …

[HTML][HTML] Colchicine resistance and intolerance in familial mediterranean fever: Definition, causes, and alternative treatments

S Ozen, I Kone-Paut, A Gül - Seminars in arthritis and rheumatism, 2017 - Elsevier
Abstract Background Familial Mediterranean Fever (FMF) is a hereditary autoinflammatory
syndrome characterized by recurrent serositis or arthritis attacks and, in some patients …

[HTML][HTML] Rhabdomyosarcoma: current therapy, challenges, and future approaches to treatment strategies

A Zarrabi, D Perrin, M Kavoosi, M Sommer, S Sezen… - Cancers, 2023 - mdpi.com
Simple Summary Rhabdomyosarcoma (RMS) is a rare pediatric sarcoma affecting skeletal
muscle in children and young adults. It is responsible for 3% of all childhood malignant …

Functional significance of genetic polymorphisms in P-glycoprotein (MDR1, ABCB1) and breast cancer resistance protein (BCRP, ABCG2)

I Ieiri - Drug metabolism and pharmacokinetics, 2012 - jstage.jst.go.jp
Recent pharmacogenomic/pharmacogenetic (PGx) studies have disclosed important roles
for drug transporters in the human body. Changes in the functions of drug transporters due …

The pharmacogenetics of natural products: A pharmacokinetic and pharmacodynamic perspective

T Rao, Z Tan, J Peng, Y Guo, Y Chen, H Zhou… - Pharmacological …, 2019 - Elsevier
Natural products have represented attractive alternatives for disease prevention and
treatment over the course of human history and have contributed to the development of …