A new landscape for malaria vaccine development
AJ Laurenson, MB Laurens - PLoS Pathogens, 2024 - journals.plos.org
On October 6, 2021, the World Health Organization (WHO) recommended the first vaccine
against malaria to prevent Plasmodium falciparum malaria in children living in areas with …
against malaria to prevent Plasmodium falciparum malaria in children living in areas with …
DNA Vaccines: Their formulations, engineering and delivery
M Kozak, J Hu - Vaccines, 2024 - mdpi.com
The concept of DNA vaccination was introduced in the early 1990s. Since then,
advancements in the augmentation of the immunogenicity of DNA vaccines have brought …
advancements in the augmentation of the immunogenicity of DNA vaccines have brought …
Immunoinformatics-driven in silico vaccine design for Nipah virus (NPV): Integrating machine learning and computational epitope prediction
The Nipah virus (NPV) is a highly lethal virus, known for its significant fatality rate. The virus
initially originated in Malaysia in 1998 and later led to outbreaks in nearby countries such as …
initially originated in Malaysia in 1998 and later led to outbreaks in nearby countries such as …
Reverse vaccinology and immunoinformatics approaches to design multi-epitope based vaccine against oncogenic KRAS
PS Ramalingam, S Arumugam - Medical Oncology, 2023 - Springer
Mutant KRAS-induced tumorigenesis is highly involved in the progression of pancreatic,
lung, and breast cancer. Comparatively, KRAS G12D and KRAS G12C are the most frequent …
lung, and breast cancer. Comparatively, KRAS G12D and KRAS G12C are the most frequent …
Reverse vaccinology and immunoinformatics approach to design a chimeric epitope vaccine against Orientia tsutsugamushi
Scrub typhus is a vector-borne infectious disease caused by Orientia tsutsugamushi and it is
reportedly associated with up to 20% of hospitalized cases of febrile illnesses. The major …
reportedly associated with up to 20% of hospitalized cases of febrile illnesses. The major …
Advancing Vaccine Strategies against Candida Infections: Exploring New Frontiers
Candida albicans, along with several non-albicans Candida species, comprise a prominent
fungal pathogen in humans, leading to candidiasis in various organs. The global impact of …
fungal pathogen in humans, leading to candidiasis in various organs. The global impact of …
Immunoinformatics approach for designing a multiepitope subunit vaccine against porcine epidemic diarrhea virus genotype IIA spike protein
Background: Porcine epidemic diarrhea (PED), caused by the porcine epidemic diarrhea
virus (PEDV), is associated with high mortality and morbidity rates, especially in neonatal …
virus (PEDV), is associated with high mortality and morbidity rates, especially in neonatal …
Advancing one health vaccination: In silico design and evaluation of a multi-epitope subunit vaccine against Nipah virus for cross-species immunization using …
The resurgence of the Nipah virus (NiV) in 2023 has raised concerns for another potentially
severe pandemic, given its history of high mortality from previous outbreaks. Unfortunately …
severe pandemic, given its history of high mortality from previous outbreaks. Unfortunately …
[HTML][HTML] Unleashing the power of colloidal gold immunochromatographic assays for plant virus diagnostics
A Ghorbani, S Astaraki, M Rostami, A Pakdel - MethodsX, 2024 - Elsevier
The colloidal gold immunochromatographic assay (GICA) has become a popular method for
the rapid detection of plant viruses. This assay format uses antibodies labeled with colloidal …
the rapid detection of plant viruses. This assay format uses antibodies labeled with colloidal …
Design of multi-epitope vaccine candidate based on OmpA, CarO and ZnuD proteins against multi-drug resistant Acinetobacter baumannii
B Negahdari, P Sarkoohi, B Shahbazi, K Ahmadi - Heliyon, 2024 - cell.com
Acinetobacter baumannii has been identified as a major cause of nosocomial infections.
Acinetobacter infections are often difficult to treat with multidrug resistant phenotypes. One of …
Acinetobacter infections are often difficult to treat with multidrug resistant phenotypes. One of …