The genus Enterovirus (EV) of the family Picornaviridae includes poliovirus,
coxsackieviruses, echoviruses, numbered enteroviruses and rhinoviruses. These diverse …

Protein–protein recognition plays an essential role in structure and function. Specific non-
covalent interactions stabilize the structure of macromolecular assemblies, exemplified in …

Lassa virus (LASV) is a human pathogen, causing substantial morbidity and mortality,.
Similar to other Arenaviridae, it presents a class-I spike complex on its surface that facilitates …

▪ Abstract Structural studies of polio-and closely related viruses have provided a series of
snapshots along their cell entry pathways. Based on the structures and related kinetic …

The activity of pleconaril in cell culture against prototypic enterovirus strains and 215 clinical
isolates of the most commonly isolated enterovirus serotypes was examined. The latter …

Respiratory synctial virus (RSV) infections are a common and concerning conundrum. This
ubiquitous agent is the major respiratory pathogen of young children, with life‐threatening …

The picornavirus family consists of a large number of small RNA viruses, many of which are
significant pathogens of humans and livestock. They are amongst the simplest of vertebrate …

Human rhinoviruses (RVs) are picornaviruses that can cause a variety of upper and lower
respiratory tract illnesses, including the common cold, bronchitis, pneumonia, and …

Background: Minute virus of mice (MVM) is a single-stranded (ss) DNA-containing, murine
parvovirus with a capsid built up of 60 icosahedrally related polypeptide chains, each of …

Upon interacting with its receptor, poliovirus undergoes conformational changes that are
implicated in cell entry, including the externalization of the viral protein VP4 and the N …