Objective The management of vascular anomalies is complex and requires a
multidisciplinary team with a combination of medical, surgical, and intervention treatments …

Arteriovenous malformations are a vascular anomaly typically present at birth, characterized
by an abnormal connection between an artery and a vein (bypassing the capillaries). These …

Lymphatic cystic malformations are rare genetic disorders mainly due to somatic gain-of-
function mutations in the PIK3CA gene. These anomalies are frequently associated with …

Vascular malformations are inborn errors of vascular morphogenesis and consist of
localized networks of abnormal blood and/or lymphatic vessels with weak endothelial cell …

Abstract The International Society for the Study of Vascular Anomalies classifies vascular
anomalies into vascular tumors and vascular malformations. Vascular tumors are neoplasms …

Somatic activating mutations of PIK3CA are associated with development of vascular
malformations (VMs). Here, we describe a microfluidic model of PIK3CA-driven VMs …

Infantile hemangioma (IH) is the most common neoplasm in children, but it may mimic other
types of vascular anomalies or nonvascular benign and malignant tumors. In most cases, the …

Vascular Malformations belong to the spectrum of orphan diseases and can involve all
segments of the vascular tree: arteries, capillaries, and veins, and similarly the lymphatic …

Malignant vascular tumors as part of the vascular anomalies spectrum are extremely rare in
children and young adults. Instead, benign vascular neoplasias are frequently encountered …

Lymphangioma is a common type of congenital vascular disease in children with a broad
spectrum of clinical manifestations. The current classification of lymphangioma by …