The present review paper focuses on the chemistry of oxidative stress mitigation by
antioxidants. Oxidative stress is understood as a lack of balance between the pro-oxidant …

Current methods to differentiate cardiomyocytes from human pluripotent stem cells (PSCs)
inadequately recapitulate complete development and result in PSC-derived cardiomyocytes …

The erasure of epigenetic modifications across the genome of somatic cells is an essential
requirement during their reprogramming into induced pluripotent stem cells (iPSCs). Vitamin …

DNA methylation plays an important role in the maintenance of genomic stability. Ten-
eleven translocation proteins (TETs) are a family of iron (Fe2+) and α-KG-dependent …

The population of cancer survivors is rapidly increasing due to improving healthcare.
However, cancer therapies often have long-term side effects. One example is cancer therapy …

Telomeres are major contributors to cell fate and aging through their involvement in cell
cycle arrest and senescence. The accelerated attrition of telomeres is associated with aging …

Throughout life, organisms are exposed to various exogenous and endogenous factors that
cause DNA damages and somatic mutations provoking genomic instability. At a young age …

Ascorbic acid is one of the most well-known nutritional supplement and antioxidant found in
fruits and vegetables. Calcium ascorbate has been developed to mitigate the gastric …

Inflammation is a double-edged sword with both detrimental and beneficial consequences.
Understanding of the mechanisms of crosstalk between the inflammatory milieu and human …

Human embryonic stem cells (hESCs) can proliferate infinitely (self-renewal) and give rise to
almost all types of somatic cells (pluripotency). Hence, understanding the molecular …