Mucoadhesive drug delivery systems are desirable as they can increase the residence time
of drugs at the site of absorption/action, provide sustained drug release and minimize the …

Diabetes mellitus is a chronic metabolic health disease affecting the homeostasis of blood
sugar levels. However, subcutaneous injection of insulin can lead to patient non …

Mucoadhesion in drug delivery systems has recently gained interest among pharmaceutical
scientists as a means of promoting dosage form residence time as well as improving …

Aqueous gels formulated using hydrophilic polymers (hydrogels) along with those based on
stimuli responsive polymers (in situ gelling or gel forming systems) continue to attract …

Mucoadhesive polymers are of growing interest in the field of drug delivery due to their
ability to interact with the body's mucosa and increase the effectiveness of the drug …

Mucus, the slimy, viscous secretion that covers epithelial surfaces throughout the body,
contains water, salts, immunoglobulins, secreted proteins, and mucin. Mucus ecretions are …

The aim of this study was to improve the properties of chitosan as excipient in drug delivery
systems by the covalent attachment of thiol moieties. This was achieved by the modification …

Mucoadhesion is defined as the adherence of a synthetic or natural polymer to a mucosal
membrane via physical or chemical interactions. Mucoadhesive materials are widely used to …

The ability of mucoadhesive polymers to produce a large increase in the resistance to
deformation when incorporated into a mucus gel, relative to when the mucus gel and test …

Studies using infrared, 1H and 13C nuclear magnetic resonance, and X-ray photoelectron
spectroscopies and differential scanning calorimetry support the hypothesis that hydrogen …