Lung cancer is the number one cause of cancer-related deaths. The malignancy is
characterized by dismal prognosis and poor clinical outcome mostly due to advanced-stage …

Lung cancer remains the leading cause of cancer-related mortality worldwide. Tobacco
consumption remains the most important risk factor. Although the prevalence of smoking has …

Sulfur mustard (SM) is a highly toxic chemical warfare agent that causes acute lung injury
(ALI) and/or acute respiratory distress syndrome (ARDS). There are no effective therapeutic …

Tobacco smoking doubles the risk of active tuberculosis (TB) and accounts for up to 20% of
all active TB cases globally. How smoking promotes lung microenvironments permissive to …

Lung adenocarcinomas (LUADs) with mutations in the K-ras oncogene display dismal
prognosis. Proinflammatory and immunomodulatory events that drive development of K-ras …

Understanding the cellular processes that underlie early lung adenocarcinoma (LUAD)
development is needed to devise intervention strategies. Here we studied 246,102 single …

Lung adenocarcinoma (LUAD) is the most common and aggressive subtype of lung cancer
with the greatest heterogeneity and aggression. Inspite of recent years' achievements in …

Background Lung cancer is one of the most lethal malignant tumors that endangers human
health. Lung adenocarcinoma (LUAD) has increased dramatically in recent decades …

While initiation is established as a critical step in tumorigenesis, the identity of the cell of
origin for lung adenocarcinoma and the mechanism controlling susceptibility to initiation …

Microbial dysbiosis has emerged as a modulator of oncogenesis and response to therapy,
particularly in lung cancer. Here, we investigate the evolution of the gut and lung …