Kidney disease is a leading cause of morbidity and mortality across the globe. Current
interventions for kidney disease include dialysis and renal transplantation, which have …

Polycystic kidney diseases (PKDs) are genetic disorders characterized by the formation and
expansion of numerous fluid-filled renal cysts, damaging normal parenchyma and often …

Melanin-like nanoparticles (MNPs) have recently emerged as valuable agents in antioxidant
therapy due to their excellent biocompatibility and potent capacity to scavenge various …

Background Kidney injury due to cold storage–associated transplantation (CST) is a major
factor determining the outcome of renal transplant, for which the role and regulation of …

Chronic kidney disease (CKD) represents a significant global health challenge, affecting
millions of individuals and leading to substantial morbidity and mortality. This review aims to …

Emerging evidence suggests a significant contribution of primary cilia to cell division and
proliferation. MicroRNAs, especially miR-17, contribute to cell cycle regulation and …

Polycystic kidney disease (PKD) is a significant cause of end-stage kidney failure and there
are few effective drugs for treating this inherited condition. Numerous aberrantly expressed …

Autosomal Dominant Polycystic Kidney Disease (ADPKD) leads to end stage kidney
disease (ESKD) through the development and expansion of multiple cysts throughout the …

Polycystin-1 (PC1) is an 11-transmembrane (TM) domain-containing protein encoded by the
PKD1 gene, the most frequently mutated gene leading to autosomal dominant polycystic …

In polycystic kidney disease (PKD), microscopic tubules expand into macroscopic cysts.
Among the world's most common genetic disorders, PKD is inherited via heterozygous loss …