Genetic testing is used widely for diagnostic, carrier and predictive testing in monogenic
diseases. Until recently, there were no genetic testing options available for multifactorial …

Hereditary cancer syndromes are inherited pathogenic genetic variants that significantly
increase the risk of developing cancer. When individuals become aware of their increased …

Background: Adoption of new digital measures for clinical trials and practice has been
hindered by lack of actionable qualitative data demonstrating relevance of these metrics to …

While genomics provides new clinical opportunities, its complexity generates uncertainties.
This systematic review aimed to summarize what is currently known about the experience of …

Purpose This study aimed to systematically review current models for communicating
polygenic scores (PGS) and psycho-behavioral outcomes of receiving PGSs. Methods …

Polygenic risk scores (PRS) are becoming increasingly available in clinical practice to
evaluate cancer risk. However, little is known about health professionals' knowledge …

Abstract Purpose Asian Americans have been understudied in the literature on genetic and
genomic services. The current study systematically identified, evaluated, and summarized …

Purpose Germline testing in pediatric cancer presents opportunities and challenges.
Understanding family perspectives, experiences, and preferences will optimize integration …

Aim This study explored the attitudes of patients with advanced cancer towards MTP and
return of results, prior to undergoing genomic testing within a research program. Methods …

Considerable progress continues to be made with regards to the value and use of disease
associated polygenic scores (PGS). PGS aim to capture a person's genetic liability to a …