Ruthenium complexes as promising candidates against lung cancer

Q Sun, Y Li, H Shi, Y Wang, J Zhang, Q Zhang - Molecules, 2021 - mdpi.com
Lung cancer is one of the most common malignancies with the highest mortality rate and the
second-highest incidence rate after breast cancer, posing a serious threat to human health …

Synthetic and medicinal perspective of antileishmanial agents: an overview

S Pawar, MK Kumawat, M Kundu, K Kumar - Journal of Molecular Structure, 2023 - Elsevier
Leishmaniasis is one of the most common neglected tropical diseases (NTD), and is
originated in over 98 countries, affecting about 12 million people every year, which is …

An appraisal of the scientific current situation and new perspectives in the treatment of cutaneous leishmaniasis

CAB Nieva, AG Cid, AI Romero, MF García-Bustos… - Acta Tropica, 2021 - Elsevier
Abstract Leishmaniasis is a Neglected Tropical Diseases caused by protozoan parasites of
the genus Leishmania. It is a major health problem in many tropical and subtropical regions …

Tunable Anticancer Activity of Furoylthiourea‐Based RuII–Arene Complexes and Their Mechanism of Action

S Swaminathan, J Haribabu… - … A European Journal, 2021 - Wiley Online Library
Fourteen new RuII–arene (p‐cymene/benzene) complexes (C1–C14) have been
synthesized by varying the N‐terminal substituent in the furoylthiourea ligand and …

Copaifera spp. oleoresins impair Toxoplasma gondii infection in both human trophoblastic cells and human placental explants

SC Teixeira, G de Souza, BC Borges, TE de Araújo… - Scientific reports, 2020 - nature.com
The combination of pyrimethamine and sulfadiazine is the standard care in cases of
congenital toxoplasmosis. However, therapy with these drugs is associated with severe and …

Metallodrugs for the treatment of trypanosomatid diseases: Recent advances and new insights

M Navarro, R Justo, GYS Delgado… - Current Pharmaceutical …, 2021 - ingentaconnect.com
Trypanosomatid parasites are responsible for many Neglected Tropical Diseases (NTDs).
NTDs are a group of illnesses that prevail in low-income populations, such as in tropical and …

Ruthenium (II) complex cis-[RuII2-O2CC7H7O2)(dppm)2]PF6-hmxbato induces ROS-mediated apoptosis in lung tumor cells producing selective …

MS Costa, YG Gonçalves, BC Borges, MJB Silva… - Scientific Reports, 2020 - nature.com
Ruthenium complexes have been extensively explored as potential molecules for cancer
treatment. Considering our previous findings on the remarkable cytotoxic activity exhibited …

In vitro and in silico anticancer potential of binuclear silver (I) N-heterocyclic carbene (NHCs) complexes: Investigation of interaction with surfactants

R Ashraf, S Akram, M El-Naggar, A Kanwal, TT Tok… - Inorganica Chimica …, 2024 - Elsevier
N-heterocyclic carbene (NHCs) silver complexes are getting tremendous attention for
appealing biological potentials. The present study is planned to synthesize silver-NHC …

Promoting the Anticancer Activity with Multidentate Furan-2-Carboxamide Functionalized Aroyl Thiourea Chelation in Binuclear Half-Sandwich Ruthenium (II) …

SK Thangavel, MS Mohamed Kasim… - Inorganic …, 2024 - ACS Publications
A new set of binuclear arene ruthenium complexes [Ru2 (p-cymene) 2 (k4-N2OS)(L1-L3)
Cl2](Ru 2 L1–Ru 2 L3) encompassing furan-2-carboxamide-based aroylthiourea derivatives …

Vanadium compounds as antiparasitic agents: An approach to their mechanisms of action

CT Brenda, RF Norma, RL Marcela, LV Nelly… - Journal of Trace …, 2023 - Elsevier
Background Parasitic infections are a public health problem since they have high morbidity
and mortality worldwide. In parasitosis such as malaria, leishmaniasis and trypanosomiasis …