Epidermal growth factor receptor (EGFR) is the first discovered member of the receptor
tyrosine kinase superfamily and plays a fundamental role during embryogenesis and in …

The epidermal growth factor receptor (EGFR) was among the first receptor tyrosine kinases
(RTKs) for which ligand binding was studied and for which the importance of ligand-induced …

Over 90% of head and neck cancers overexpress the epidermal growth factor receptor
(EGFR). In diverse tumor types, EGFR overexpression has been associated with poorer …

What is the relationship between the wound-healing process and the development of
cancer? Malignant tumours often develop at sites of chronic injury, and tissue injury has an …

The epidermal growth factor receptor (EGFR) is the prototypical member of a family of
membrane-associated intrinsic tyrosine kinase receptors, the ErbB family. EGFR is activated …

Persistent inflammation is known to promote and exacerbate malignancy. Primary liver
cancer, mostly hepatocellular carcinoma (HCC), is a clear example of inflammation-related …

Epidermal growth factor receptor (EGFR), a receptor tyrosine kinase, is activated by ligand
binding, overexpression, or mutation. It is well known for its tyrosine kinase-dependent …

The epidermal growth factor receptor (EGFR) is a transmembrane receptor tyrosine kinase
that is activated by several ligands leading to the activation of diverse signaling pathways …

EGFR and Hippo signaling pathways both control growth and, when dysregulated,
contribute to tumorigenesis. We find that EGFR activates the Hippo pathway transcription …

Extracellular signal-regulated kinase (ERK) is a key effector of many growth signalling
pathways. In this study, we visualise epidermal ERK activity in living mice using an ERK …