The article reviews applications of flow cytometry sorting in manufacturing of
pharmaceuticals. Flow cytometry sorting is an extremely powerful tool for monitoring …

CRISPR-Cas technology, discovered originally as a bacterial defense system, has been
extensively repurposed as a powerful tool for genome editing for multiple applications in …

Introduction Gene-editing technology revolutionized vaccine manufacturing and offers a
variety of benefits over traditional vaccinations, such as improved immune response, higher …

The Sf9 cell line, originally isolated from the insect Spodoptera frugiperda, is commonly
used alongside the baculovirus expression vector system (BEVS) to produce recombinant …

Viral replication and transmissibility are the principal causes of endemic and pandemic
disease threats. There remains a need for broad-spectrum antiviral agents. The most …

Since the widespread introduction of oral and live attenuated rotavirus vaccines around the
world in 2009, the impacts of disease burden and the effects of disease reduction in …

Human norovirus (HuNoV) is a principal cause of acute gastroenteritis worldwide,
particularly in developing countries. Its global prevalence is underscored by more serious …

Every year, millions of children are infected with viruses that target the gastrointestinal tract,
causing acute gastroenteritis and diarrheal illness. Indeed, approximately 700 million …

Group A rotavirus (RVA) is a major cause of severe gastroenteritis in infants and young
children globally, despite the availability of live‐attenuated vaccines. Challenges such as …

Despite their wide use in the vaccine manufacturing field for over 40 years, one of the main
limitations to recent efforts to develop Vero cells as high‐throughput vaccine manufacturing …