The base pairs in double helical nucleic acids have been compared to see how they can be
recognized by proteins. We conclude that a single hydrogen bond is inadequate for uniquely …

Transcription factors (TFs) intricately navigate the vast genomic landscape to locate and
bind specific DNA sequences for the regulation of gene expression programs. These …

There is much interest in the design and synthesis of chemical compounds that possess
binding specificity comparable with that of bacterial repressors. These compounds could be …

1. Introduction The selective association of nucleic acids with proteins is of utmost
importance at every step of genetic expression. The most striking examples include the …

Interaction of DNA with the analogs of the antibiotic distamycin A having different numbers of
pyrrolcarboxamide groups and labeled with dansyl was studied. The binding isoterms of the …

The specificity of binding interactions between regulatory proteins and DNA is a
consequence of cqmplementarity between the sequences of specific reaction centers on the …

The review demonstrates an application of methods of statistical thermodynamics for the
analysis of binding of ligands to DNA and RNA. Reversible binding of ligands to nucleic …

The crystal structure of 3-(adenin-9-yl) propiontryptamide (3-(adenin-9-yl)-N-[2-(3-indolyl)
ethyl] propionamide) has been investigated as a model for adenine-tryptophan interaction …

Разработан новый метод анализа непосредственных ДНК-белковых контактов па
основе разбиения Вороного. На основе изучения 1109 комплексов белок-ДНК из банка …

A model for stereospecific complex between a polynucleotide double helix and a twisted β-
ribbon type polypeptide is described. The β ribbon lies in the major groove with alternate …