Many ways to Rome: exercise, cold exposure and diet—do they all affect BAT activation and WAT browning in the same manner?

AK Scheel, L Espelage, A Chadt - International journal of molecular …, 2022 - mdpi.com
The discovery of functional brown adipose tissue (BAT) in adult humans and the possibility
to recruit beige cells with high thermogenic potential within white adipose tissue (WAT) …

Bone marrow adipose tissue is a unique adipose subtype with distinct roles in glucose homeostasis

KJ Suchacki, AAS Tavares, D Mattiucci… - Nature …, 2020 - nature.com
Bone marrow adipose tissue (BMAT) comprises> 10% of total adipose mass, yet unlike
white or brown adipose tissues (WAT or BAT) its metabolic functions remain unclear. Herein …

Brown and white adipose tissues: intrinsic differences in gene expression and response to cold exposure in mice

M Rosell, M Kaforou, A Frontini… - American Journal …, 2014 - journals.physiology.org
Brown adipocytes dissipate energy, whereas white adipocytes are an energy storage site.
We explored the plasticity of different white adipose tissue depots in acquiring a brown …

[HTML][HTML] Cardiolipin synthesis in brown and beige fat mitochondria is essential for systemic energy homeostasis

EG Sustarsic, T Ma, MD Lynes, M Larsen, I Karavaeva… - Cell metabolism, 2018 - cell.com
Activation of energy expenditure in thermogenic fat is a promising strategy to improve
metabolic health, yet the dynamic processes that evoke this response are poorly …

Host genetic selection for cold tolerance shapes microbiome composition and modulates its response to temperature

F Kokou, G Sasson, T Nitzan, A Doron-Faigenboim… - elife, 2018 - elifesciences.org
The hologenome concept proposes that microbes and their host organism are an
independent unit of selection. Motivated by this concept, we hypothesized that thermal …

Cold-induced lipid dynamics and transcriptional programs in white adipose tissue

Z Xu, W You, Y Zhou, W Chen, Y Wang, T Shan - BMC biology, 2019 - Springer
Background In mammals, cold exposure induces browning of white adipose tissue (WAT)
and alters WAT gene expression and lipid metabolism to boost adaptive thermogenesis and …

Cold-hearted: A case for cold stress in cancer risk

S Bandyopadhayaya, B Ford, CC Mandal - Journal of Thermal Biology, 2020 - Elsevier
A negative correlation exists between environmental temperature and cancer risk based on
both epidemiological and statistical analyses. Previously, cold stress was reported to be an …

Transcriptome profiling of brown adipose tissue during cold exposure reveals extensive regulation of glucose metabolism

Q Hao, R Yadav, AL Basse… - American Journal …, 2015 - journals.physiology.org
We applied digital gene expression profiling to determine the transcriptome of brown and
white adipose tissues (BAT and WAT, respectively) during cold exposure. Male C57BL/6J …

Cold exposure induces lipid dynamics and thermogenesis in brown adipose tissue of goats

X Liu, J Tang, R Zhang, S Zhan, T Zhong, J Guo… - BMC genomics, 2022 - Springer
Background Adaptive thermogenesis by brown adipose tissue (BAT) is important to the
maintenance of temperature in newborn mammals. Cold exposure activates gene …

Maternal high-fat diet during lactation impairs thermogenic function of brown adipose tissue in offspring mice

X Liang, Q Yang, L Zhang, JW Maricelli, BD Rodgers… - Scientific reports, 2016 - nature.com
Maternal obesity and high-fat diet (HFD) predisposes offspring to obesity and metabolic
diseases. Due to uncoupling, brown adipose tissue (BAT) dissipates energy via heat …