Design, optimization, and nanotechnology of antimicrobial peptides: From exploration to applications

P Tan, H Fu, X Ma - Nano Today, 2021 - Elsevier
Antibiotic resistance caused by antibiotic abuse, especially the emergence of multi-drug
resistant bacteria, poses a serious threat to human health, and makes it imperative to find …

Recent innovations in bacterial infection detection and treatment

C Deusenbery, Y Wang, A Shukla - ACS Infectious Diseases, 2021 - ACS Publications
Bacterial infections are a major threat to human health, exacerbated by increasing antibiotic
resistance. These infections can result in tremendous morbidity and mortality, emphasizing …

Addressing MRSA infection and antibacterial resistance with peptoid polymers

J Xie, M Zhou, Y Qian, Z Cong, S Chen… - Nature …, 2021 - nature.com
Abstract Methicillin-Resistant Staphylococcus aureus (MRSA) induced infection calls for
antibacterial agents that are not prone to antimicrobial resistance. We prepare protease …

High antibacterial activity and selectivity of the versatile polysulfoniums that combat drug resistance

J Sun, M Li, M Lin, B Zhang, X Chen - Advanced Materials, 2021 - Wiley Online Library
Sulfonium‐ion‐containing polymers exhibit significant potential benefits for various
applications. An efficient strategy to synthesize a type of antibacterial sulfonium‐ion‐bearing …

Recent progress in photocatalytic antibacterial

Z Zhou, B Li, X Liu, Z Li, S Zhu, Y Liang… - ACS Applied Bio …, 2021 - ACS Publications
Pathogens on wounds and infected tissues or pathogens in drinking water or public facilities
have been doing great harm in human life. Because of booming drug resistance and …

[HTML][HTML] Therapeutic strategies against bacterial biofilms

Y Bi, G Xia, C Shi, J Wan, L Liu, Y Chen, Y Wu… - Fundamental …, 2021 - Elsevier
The emergence of multi-drug resistance makes bacterial infection a major threat to public
health and economy. The formation of bacterial biofilms is one of the main reasons of …

Host defense peptide mimicking antimicrobial amino acid polymers and beyond: Design, synthesis and biomedical applications

Y Wu, K Chen, J Wang, M Chen, Y Chen, Y She… - Progress in Polymer …, 2023 - Elsevier
Microbial infections endanger human health and life. Conventional antibiotics has saved
countless human lives, however, is seriously challenged by the quick emergence of …

Poly (2‐Oxazoline)‐based functional peptide mimics: Eradicating MRSA infections and persisters while alleviating antimicrobial resistance

M Zhou, Y Qian, J Xie, W Zhang… - Angewandte Chemie …, 2020 - Wiley Online Library
Peptides have important biological functions. However, their susceptibility to proteolysis
limits their applications. We demonstrated here for the first time, that poly (2 …

Beyond nylon 6: Polyamides via ring opening polymerization of designer lactam monomers for biomedical applications

M Varghese, MW Grinstaff - Chemical Society Reviews, 2022 - pubs.rsc.org
Ring opening polymerization (ROP) of lactams is a highly efficient and versatile method to
synthesize polyamides. Within the last ten years, significant advances in polymerization …

Antimicrobial peptides and macromolecules for combating microbial infections: from agents to interfaces

L Yu, K Li, J Zhang, H Jin, A Saleem… - ACS Applied Bio …, 2022 - ACS Publications
Bacterial resistance caused by the overuse of antibiotics and the shelter of biofilms has
evolved into a global health crisis, which drives researchers to continuously explore …