Carcinoma of the breast is the most prevalent cancer among Egyptian women and
constitutes 29% of National Cancer Institute cases. Median age at diagnosis is one decade …

The molecular mechanisms underlying the development of breast cancer in general, and
estrogen-associated breast carcinogenesis in particular, are not completely understood …

Colorectal cancer is the third most common cancer in males and second in females. This
disease can be caused by genetic and acquired/environmental factors. Microsatellite …

AIM: DNA mismatch repair (MMR) is an important mechanism for maintaining fidelity of
genomic DNA. Abnormalities in one or more MMR genes are implicated in the development …

We have characterized the role of genetic alterations in the development of liver fluke
related cholangiocarcinoma. We analyzed the loss of heterozygosity (LOH) and …

Purpose: The purpose is to define molecular prognostic factors in patients with advanced
breast cancer treated with high-dose chemotherapy (HDCT) and autologous stem cell …

Background: Carcinoma of the urinary bladder is the most common malignancy in Egypt in
which infection with Schistosoma haematobium is prevalent. This type of malignancy has …

BACKGROUND The positive replication error (RER+) phenotype defines a distinct subgroup
of tumors with specific clinical, pathologic, and molecular features that have been …

ABSTRACT DNA mismatch repair (MMR) is an important mechanism involved in
maintaining fidelity of genomic DNA. Defective MMR is implicated in a variety of tumors; …

Résumé Le cancer du sein est caractérisé par une instabilité génétique importante générant
de fréquentes pertes d'allèles (LOH: loss of heterozygosity) et beaucoup plus rarement des …