Three-dimensional (3D) printing is an additive manufacturing technique that creates objects
under computer control. Owing to the rapid advancement of science and technology, 3D …

The oral mucosa is a versatile surface for drug administration, supporting both local and
systemic therapies. Many active substances are effectively absorbed in the oral cavity …

This study demonstrated the implementation of a liquisolid technique to formulate directly
compressible orally disintegrating tablets (ODTs). Cannabidiol (CBD), a hydrophobic …

The present study aimed to develop fast melting tablets (FMTs) using silymarin (SM) owing
to FMTs rapid disintegration and dissolution. FMTs represent a pathway to help patients to …

The low and erratic oral absorption of sulpiride (SUL) a dopaminergic receptor antagonist,
and its P-glycoprotein efflux in the gastrointestinal tract restricted its oral route for central …

There are challenges to implementing high-speed direct compression tableting for poor flow,
low-density cohesive powder. Thus, excipients with adequate flowability and bulk density …

The current study aims to develop orodispersible lyophilisates (ODLs), containing
olmesartan medoxomil (OLM), by applying a quality by design approach to ensure product …

This study aims at developing new multicomponent crystal forms of sulpiride, an
antipsychotic drug. The main goal was to improve its solubility since it belongs to class IV of …

The interaction between meloxicam and sulfonatocalix [4] naphthalene was investigated to
improve the meloxicam solubility and its dissolution performance. Solubility behavior was …

Oromucosal delivery of olanzapine (OLZ) is an optimal strategy to overcome low oral
bioavailability as well as improve medication adherence. However, its poor aqueous …