Serum response factor (SRF) is a representative transcription factor that plays crucial roles
in various biological phenomena by regulating immediate early genes (IEGs) and genes …

Modulating neuronal behavior via topographical cues is integral to studying neuronal
development, building in vitro neural networks, and designing better neural interfaces and …

The growth cone, a motile structure located at the tip of growing axons, senses extracellular
guidance cues and translates them into directional forces that drive axon outgrowth and …

As an element of the cellular signaling systems, extracellular vesicles (EVs) exhibit many
desirable traits for usage as targeted delivery vehicles. When administered, EVs cause little …

Mechanical cues from the tissue microenvironment, such as the stiffness of the extracellular
matrix, modulate cellular forms and functions. As numerous studies have shown, this …

Background: Physical activity has been recently shown to enhance adult visual cortical
plasticity, both in human subjects and animal models. While physical activity activates …

Background Atherosclerosis (AS) is a pathology factor for cardiovascular diseases and
instability of atherosclerotic plaques contributes to acute coronary events. This study …

Gene cis-regulatory sequences are increasingly recognised as containing" domesticated"
transposable elements that impact their function. The KRAB Zinc Finger Protein (KZFP) …

The focal adhesion (FA) is the structural basis of the cell-extracellular matrix crosstalk and
plays important roles in control of organ formation and function. Here we show that …

Cell adhesion, a process underlying the maintenance and development of multicellularity, is
fundamentally dependent on the activity of talin as a mechanosensitive signalling nexus …