Colorectal cancer (CRC) is one of the most frequently occurring malignancy tumors with a
high morbidity additionally, CRC patients may develop liver metastasis, which is the major …

Colorectal cancer (CRC) is the third most common cancer and the fourth most common
cause of cancer-related death. Most cases of CRC are detected in Western countries, with its …

Abstract microRNAs (miRNAs) play critical roles in cancer development and progression.
This study investigated the effects of miR-138-5p in human colorectal cancer (CRC) …

MicroRNAs (miRNAs) are small single-stranded RNAs that repress mRNA translation and
trigger mRNA degradation. Of the∼ 1900 miRNA-encoding genes present in the human …

Colorectal cancer (CRC) is one of the deadliest human malignancies worldwide. Several
molecular pathways have been demonstrated to be involved in the initiation and …

Regulation of microRNA (miRNA) expression has been extensively studied with respect to
colorectal cancer (CRC), since CRC is one of the leading causes of cancer mortality …

Long non-coding RNAs (lncRNAs) play key roles in various malignant tumors, including
colorectal cancer (CRC). Long non-coding RNA differentiation antagonizing non-protein …

The discovery of microRNAs (miRNAs) 20 years ago has advocated a new era of “small
molecular genetics.” About 2000 miRNAs are present that regulate one third of the genome …

Mechanistic target of rapamycin (mTOR) is a conserved serine/threonine kinase that plays a
critical role in the control of cellular growth and metabolism. Hyperactivation of mTOR …

Colorectal cancer (CRC), ranking as the third commonest cancer, leads to extremely high
rates of mortality. Metastasis is the major cause of poor outcome in CRC. When metastasis …