DNA-damaging agents and endogenous DNA damage constantly harm genome integrity.
Under genotoxic stress conditions, the DNA damage response (DDR) machinery is crucial in …

Background Brain development during embryogenesis and in early postnatal life is
particularly complex and involves the interplay of many cellular processes and molecular …

Abstract Cockayne Syndrome B (CSB) is a hereditary multiorgan syndrome which—through
largely unknown mechanisms—can affect the brain where it clinically presents with …

Adverse Outcome Pathways (AOPs) are useful tools for assessing the potential risks
associated with exposure to various stressors, including chemicals and environmental …

Malformations of cortical development (MCD) are structural anomalies that disrupt the
normal process of cortical development. Patients with these anomalies frequently present …

Some studies relate the use of pyriproxyfen (PPF) in drinking water with damage to
embryonic neurodevelopment, including a supposed association with cases of …

Objectives: To comprehensively evaluate the contributions of numerical chromosomal
abnormality, copy number variant (CNV), and sequence variant (SV) to fetuses with small …

One of the most common definitions of microcephaly cited is that of an occipitofrontal
circumference (OFC) of the head that is less than two standard deviations below the average …

Pyriproxyfen (PPF), Bacillus thuringiensis israelensis (BTI), and malathion (MLT) are widely
used worldwide to control the population of mosquitos that transmit arboviruses. The current …

Background/Objectives: This study aimed to explore a relationship between the fetal
subarachnoid space (SAS) width and various fetal pathologies, employing fetal brain MRI …