Acute cannabinoids produce robust anxiety-like and locomotor effects in mice, but long-term consequences are age-and sex-dependent

CR Kasten, Y Zhang, SL Boehm - Frontiers in behavioral …, 2019 - frontiersin.org
The rise in cannabinoid legalization and decriminalization in the US has been paired with
an increase in adolescents that perceive marijuana as a “no risk” drug. However, a …

Cannabinoids, interoception, and anxiety

AK Andrade, B Renda, JE Murray - Pharmacology Biochemistry and …, 2019 - Elsevier
The use of cannabis is rapidly gaining legal status across North America. Such dramatic
legislative shifts have prompted an urgency in elucidating the stimulus effects of cannabis …

Sex and strain variation in initial sensitivity and rapid tolerance to Δ9–tetrahydrocannabinol

C Parks, BC Jones, BM Moore… - Cannabis and …, 2020 - liebertpub.com
Background and Objectives: For cannabis and other drugs of abuse, initial response and/or
tolerance to drug effects can predict later dependence and problematic use. Our objective is …

Impact of early-life lead exposure on adult delta-9-tetrahydrocannabinol sensitivity in male and female C57BL6/J mice

D Garcy, SL Boehm II - Neurotoxicology and Teratology, 2023 - Elsevier
Environmental exposure to lead (Pb) and cannabis use are two of the largest public health
issues facing modern society in the United States and around the world. Exposure to Pb in …

Genetic factors in cannabinoid use and dependence

MK Mulligan - Recent Advances in Cannabinoid Physiology and …, 2019 - Springer
Cannabinoid use and dependence are heritable traits controlled in part by genetic factors.
Despite a high incidence of use worldwide, genes that contribute to the risk of problematic …

Cannabis Pharmacogenetics in Mice

K Lanier - 2024 - search.proquest.com
For centuries, Cannabis has been utilized for various purposes, notably as a remedy for
numerous ailments. Despite challenges faced in the legal realm, medical applications …

Is there Evidence of a Genetic Basis for Substance Use Disorders?

S Schenk - Psychobiological Issues in Substance Use and …, 2020 - taylorfrancis.com
This chapter reviews the evidence supporting a genetic basis of drug addiction. The
evidence from twin studies, genome-wide association studies and from animal studies is …

The Effects of Early-Life Lead Exposure on Adult Delta-9-Tetrahydrocannabinol Sensitivity, Self-Administration, and Tolerance

D Garcy - 2022 - search.proquest.com
Environmental exposure to lead (Pb) and cannabis use are two of the largest public health
issues facing modern society in the United States and around the world. Exposure to Pb in …

[图书][B] Genetic Variation and Sex Mediate Differential Responses to∆-9-tetrahydrocannabinol among Inbred Mice

C Parks - 2020 - search.proquest.com
The plant Cannabis sativa has been used by people for both recreational and medicinal use
for thousands of years, but scientific investigation of the plant and its components didn't …

[图书][B] Potentialet af Cannabis: Opslagsværk med dokumenteret viden om en medicinsk plante i høje tider

H Christensen - 2021 - books.google.com
Potentialet af cannabis er en dokumenteret og videnskabelig bog om cannabisplantens
aktive indholdsstoffer og medicinske egenskaber, hvordan cannabisprodukter fremstilles og …