Malaria vaccines: from the past towards the mRNA vaccine era

ME Tsoumani, C Voyiatzaki, A Efstathiou - Vaccines, 2023 - mdpi.com
Plasmodium spp. is the etiological agent of malaria, a life-threatening parasitic disease
transmitted by infected mosquitoes. Malaria remains a major global health challenge …

Chitosan-based nanomaterial as immune adjuvant and delivery carrier for vaccines

X Gong, Y Gao, J Shu, C Zhang, K Zhao - Vaccines, 2022 - mdpi.com
With the support of modern biotechnology, vaccine technology continues to iterate. The
safety and efficacy of vaccines are some of the most important areas of development in the …

An arabinogalactan extracted with alkali from Portulaca oleracea L. used as an immunopotentiator and a vaccine carrier in its conjugate to BSA

Y Yang, H Li, F Wang, P Jiang, G Wang - Carbohydrate Polymers, 2023 - Elsevier
A neutral polysaccharide (POPAN) from Portulaca oleracea L. was isolated with alkali and
purified to obtain. HPLC analysis suggested POPAN (40.9 kDa) was mainly composed of …

[HTML][HTML] CRISPR/Cas advancements for genome editing, diagnosis, therapeutics, and vaccine development for Plasmodium parasites, and genetic engineering of …

L Nourani, AA Mehrizi, S Pirahmadi… - Infection, Genetics and …, 2023 - Elsevier
Malaria as vector-borne disease remains important health concern with over 200 million
cases globally. Novel antimalarial medicines and more effective vaccines must be …

The antimalarial activity of 1, 2, 4‐trioxolane/trioxane hybrids and dimers: a review

J Fang, F Song, F Wang - Archiv der Pharmazie, 2022 - Wiley Online Library
Malaria, a mosquito‐borne parasitic infection caused by protozoan parasites belonging to
the genus Plasmodium, is a dangerous disease that contributes to millions of hospital visits …

[HTML][HTML] Gene expression analysis of Anopheles Meigen, 1818 (Diptera: Culicidae) innate immunity after Plasmodium Marchiafava & Celli, 1885 (Apicomplexa) …

ZS Mousavi, ZM Firouz, S Pirahmadi - Infection, Genetics and Evolution, 2024 - Elsevier
Despite the critical role of the Anopheles innate immune system in defending against
Plasmodium infection, there is still limited information about the key immune mechanisms in …

Mining gene expression data for rational identification of novel drug targets and vaccine candidates against the cattle tick, Rhipicephalus microplus

C Maritz-Olivier, M Ferreira, NA Olivier… - … and Applied Acarology, 2023 - Springer
Control of complex parasites via vaccination remains challenging, with the current
combination of vaccines and small drugs remaining the choice for an integrated control …

Recombinant VLP Vaccines Synthesized in Plant Expression Systems: Current Updates and Prospects

SM Rozov, EV Deineko - Molecular Biology, 2024 - Springer
The development and creation of a new generation vaccines based on recombinant proteins
that assemble into virus-like particles (VLPs), as well as recombinant proteins in the form of …

Investigating protective mechanisms of anti-sporozoite vaccines

DG Bellamy - 2023 - ora.ox.ac.uk
Malaria remains a leading cause of childhood mortality, thereby highlighting the need for an
effective vaccine. R21 is a virus-like particle-based (VLP-based) vaccine displaying the …

[PDF][PDF] Malaria Vaccines: From the Past towards the mRNA Vaccine Era. Vaccines 2023, 11, 1452

ME Tsoumani, C Voyiatzaki, A Efstathiou - 2023 - academia.edu
Plasmodium spp. is the etiological agent of malaria, a life-threatening parasitic disease
transmitted by infected mosquitoes. Malaria remains a major global health challenge …