Regulation of placental extravillous trophoblasts by the maternal uterine environment

J Pollheimer, S Vondra, J Baltayeva… - Frontiers in …, 2018 - frontiersin.org
During placentation invasive extravillous trophoblasts (EVTs) migrate into the maternal
uterus and modify its vessels. In particular, remodeling of the spiral arteries by EVTs is …

Growth and function of the normal human placenta

NM Gude, CT Roberts, B Kalionis, RG King - Thrombosis research, 2004 - Elsevier
The placenta is the highly specialised organ of pregnancy that supports the normal growth
and development of the fetus. Growth and function of the placenta are precisely regulated …

The decidua—the maternal bed embracing the embryo—maintains the pregnancy

M Mori, A Bogdan, T Balassa, T Csabai… - Seminars in …, 2016 - Springer
The decidua has been known as maternal uterine tissue, which plays essential roles in
protecting the embryo from being attacked by maternal immune cells and provides …

Endocrine regulation of human fetal growth: the role of the mother, placenta, and fetus

VE Murphy, R Smith, WB Giles, VL Clifton - Endocrine reviews, 2006 - academic.oup.com
The environment in which the fetus develops is critical for its survival and long-term health.
The regulation of normal human fetal growth involves many multidirectional interactions …

Extracellular vesicles secreted by human uterine stromal cells regulate decidualization, angiogenesis, and trophoblast differentiation

Q Ma, JR Beal, A Bhurke, A Kannan… - Proceedings of the …, 2022 - National Acad Sciences
In humans, the uterus undergoes a dramatic transformation to form an endometrial stroma-
derived secretory tissue, termed decidua, during early pregnancy. The decidua secretes …

Placental phenotype and the insulin‐like growth factors: resource allocation to fetal growth

AN Sferruzzi‐Perri, I Sandovici… - The Journal of …, 2017 - Wiley Online Library
The placenta is the main determinant of fetal growth and development in utero. It supplies all
the nutrients and oxygen required for fetal growth and secretes hormones that facilitate …

Human trophoblast function during the implantation process

E Staun-Ram, E Shalev - Reproductive Biology and Endocrinology, 2005 - Springer
The implantation process involves complex and synchronized molecular and cellular events
between the uterus and the implanting embryo. These events are regulated by paracrine …

The role of growth factors and cytokines during implantation: endocrine and paracrine interactions

O Guzeloglu-Kayisli, UA Kayisli… - … in reproductive medicine, 2009 - thieme-connect.com
Implantation, a critical step for establishing pregnancy, requires molecular and cellular
events resulting in uterine growth and differentiation, blastocyst adhesion, invasion, and …

Uterine leukocytes and decidualization

A King - Human reproduction update, 2000 - academic.oup.com
The transformation of endometrium into decidua is an essential feature of normal
implantation and pregnancy. There is a close association with an unusual leukocyte …

Control of human trophoblast function

L Lunghi, ME Ferretti, S Medici, C Biondi… - Reproductive Biology and …, 2007 - Springer
The trophoblast, ie the peripheral part of the human conceptus, exerts a crucial role in
implantation and placentation. Both processes properly occur as a consequence of an …