Cannabis has a long history of anecdotal medicinal use and limited licensed medicinal use. Until recently, alleged clinical effects from anecdotal reports and the use of licensed …
BJ Neth, S Craft - Frontiers in aging neuroscience, 2017 - frontiersin.org
Metabolic dysfunction is a well-established feature of Alzheimer's disease (AD), evidenced by brain glucose hypometabolism that can be observed potentially decades prior to the …
CC Leslie - Journal of lipid research, 2015 - ASBMB
The group IV phospholipase A 2 (PLA 2) family is comprised of six intracellular enzymes (GIVA,-B,-C,-D,-E, and-F) commonly referred to as cytosolic PLA 2 (cPLA 2) α,-β,-γ,-δ,-ε, and …
SG Jarrett, ME Boulton - Molecular aspects of medicine, 2012 - Elsevier
The retina resides in an environment that is primed for the generation of reactive oxygen species (ROS) and resultant oxidative damage. The retina is one of the highest oxygen …
AI Antoniou, S Giofrè, P Seneci, D Passarella… - Drug discovery today, 2021 - Elsevier
Liposomes are amphipathic lipidic supramolecular aggregates that are able to encapsulate and carry molecules of both hydrophilic and hydrophobic nature. They have been widely …
Docosahexaenoic acid (DHA) is the most abundant n-3 polyunsaturated fatty acid in the brain where it serves to regulate several important processes and, in addition, serves as a …
Importance Genome-wide investigations provide systematic information regarding the neurobiology of psychiatric disorders. Objective To identify biological pathways that …
Activated choline metabolism is a hallmark of carcinogenesis and tumor progression, which leads to elevated levels of phosphocholine and glycerophosphocholine in all types of …
X Cheng, YL Yang, H Yang, YH Wang… - International …, 2018 - Elsevier
Kaempferol is a natural flavonoid with many biological activities including anti-oxidation and anti-inflammation. Nevertheless, its anti-neuroinflammation role and the relevant mechanism …