Mast cells as sources of cytokines, chemokines, and growth factors

K Mukai, M Tsai, H Saito, SJ Galli - Immunological reviews, 2018 - Wiley Online Library
Mast cells are hematopoietic cells that reside in virtually all vascularized tissues and that
represent potential sources of a wide variety of biologically active secreted products …

Mast-cell responses to pathogens

JS Marshall - Nature Reviews Immunology, 2004 - nature.com
Mast cells have mainly been studied in the setting of allergic disease, but the importance of
mast cells for host defence against several pathogens has now been well established. The …

Differential release of mast cell mediators and the pathogenesis of inflammation

TC Theoharides, D Kempuraj, M Tagen… - Immunological …, 2007 - Wiley Online Library
Mast cells are well known for their involvement in allergic and anaphylactic reactions, during
which immunoglobulin E (IgE) receptor (FcɛRI) aggregation leads to exocytosis of the …

Mast cells as sentinels of innate immunity

SJ Galli, M Maurer, CS Lantz - Current opinion in immunology, 1999 - Elsevier
Mast cells are widely regarded as important effector cells in immune responses associated
with Th2 cells and IgE. Recent work shows that they can also contribute significantly to the …

The critical role of mast cells in allergy and inflammation

TC Theoharides… - Annals of the new York …, 2006 - Wiley Online Library
Mast cells are well known for their involvement in allergic and anaphylactic reactions, but
recent findings implicate them in a variety of inflammatory diseases affecting different …

Toll-like receptor 4-mediated activation of murine mast cells

JD McCurdy, TJ Lin, JS Marshall - Journal of leukocyte biology, 2001 - academic.oup.com
Toll-like receptors (TLRs) are a family of pattern recognition receptors that are critical for
cellular responses to a variety of bacterial, viral, and fungal products. Mast cells are …

Mast cell secretome: Soluble and vesicular components

KV Vukman, A Försönits, A Oszvald, EA Toth… - Seminars in Cell & …, 2017 - Elsevier
Mast cells are multifunctional master cells implicated in both innate and adaptive immune
responses. Their role has been best characterized in allergy and anaphylaxis; however …

Chronic peripheral administration of corticotropin-releasing factor causes colonic barrier dysfunction similar to psychological stress

AA Teitelbaum, MG Gareau, J Jury… - American Journal …, 2008 - journals.physiology.org
Chronic psychological stress causes intestinal barrier dysfunction and impairs host defense
mechanisms mediated by corticotrophin-releasing factor (CRF) and mast cells; however, the …

IFN-γ is produced by polymorphonuclear neutrophils in human uterine endometrium and by cultured peripheral blood polymorphonuclear neutrophils

GR Yeaman, JE Collins, JK Currie… - The Journal of …, 1998 - journals.aai.org
Cytokines present in the human uterus play an important role both in modulating immune
responses to infectious challenge and in the establishment and maintenance of pregnancy …

Human mast cells produce IL-13 by high-affinity IgE receptor cross-linking: Enhanced IL-13 production by IL-4–primed human mast cells

H Toru, R Pawankar, C Ra, J Yata… - Journal of Allergy and …, 1998 - Elsevier
Background: Mast cells play a central role not only in the early phase of the allergic reaction,
but also participate in the late phase of the allergic reaction through the allergen and IgE …