Prolonged low-grade inflammation or smoldering inflammation is a hallmark of cancer. Mast
cells form a heterogeneous population of immune cells with differences in their ultra …

Gastric cancer is diagnosed in nearly one million new patients each year and it remains the
second leading cause of cancer-related deaths worldwide. Although gastric cancer …

Mast cells are unique tissue‐resident immune cells that secrete a diverse array of
biologically active compounds that can stimulate, modulate, or suppress the immune …

Mast cells and basophils are key contributors to allergies and other inflammatory diseases
since they are the most prominent source of histamine as well as numerous additional …

The pathophysiological roles of mast cells are still not fully understood, over 140 years since
their description by Paul Ehrlich in 1878. Initial studies have attempted to identify distinct …

The characteristics of the tumour cells, as well as how tumour cells interact with their
surroundings, affect the prognosis of cancer patients. The resident cells in the tumour …

Background Mast cells are prominent components of solid tumors and exhibit distinct
phenotypes in different tumor microenvironments. However, the nature, regulation, function …

Angiogenesis is a complex process finely regulated by the balance between angiogenesis
stimulators and inhibitors. As a result of proangiogenic factors overexpression, it plays a …

Mast cells (MCs), a type of innate immune cells, are derived from myeloid stem cells,
sometimes known as mastocytes or labrocytes, and contain many granules rich in histamine …

Colorectal cancer (CRC) is a heterogeneous disease, molecularly and anatomically, that
develops in a multi-step process requiring the accumulation of several genetic or epigenetic …