Randomness is intrinsic to many natural processes. It is also clear that, under certain
conditions, disorders are not associated with functionality. Several examples in which …

A current challenge in cell motility studies is to understand the molecular and physical
mechanisms that govern chemokine receptor nanoscale organization at the cell membrane …

Single-particle tracking: connecting the dots | Nature Methods Skip to main content Thank you
for visiting nature.com. You are using a browser version with limited support for CSS. To obtain …

Intracellular lipid metabolism mainly occurs in lipid droplets (LDs). LDs are cytosolic lipid
storage organelles found in nearly all cell types, which dynamically change in response to …

Single-particle tracking (SPT) is widely used to study processes from membrane receptor
organization to the dynamics of RNAs in living cells. While single-dye labeling strategies …

G-protein coupled receptors (GPCRs) are the largest family of cell surface receptors; they
activate heterotrimeric G-proteins in response to ligand stimulation. Although many GPCRs …

Single-molecule localization and tracking has been used to translate spatiotemporal
information of individual molecules to map their diffusion behaviours. However, accurate …

G protein-coupled receptors (GPCRs) are important membrane proteins in higher
eukaryotes that carry out a vast array of cellular signaling and act as major drug targets. The …

Lateral diffusion enables efficient interactions between membrane proteins, leading to signal
transmission across the plasma membrane. An open question is how the spatiotemporal …

Techniques for analyzing the membrane diffusion of molecules are the most promising
methods for investigating the compartmentalization of G-protein-coupled receptors …