The aims of severe perioperative bleeding management are three-fold. First, preoperative
identification by anamesis and laboratory testing of those patients for whom the …

Object Brain edema resulting from traumatic brain injury (TBI) or ischemia if uncontrolled
exhausts volume reserve and leads to raised intracranial pressure and brain herniation. The …

Background and Purpose—Intracerebral hemorrhage (ICH) is the most serious and
potentially fatal complication of oral anticoagulant therapy (OAT). Still, there are no …

Spontaneous intracerebral hemorrhage (SICH) is a blood clot that arises in the brain
parenchyma in the absence of trauma or surgery. This entity accounts for 10 to 15% of all …

Abnormalities in blood coagulation, although quite common after traumatic brain injury (TBI),
are of unknown significance. The authors review the clinical and pathophysiological features …

Background and Purpose—Hematoma growth occurs in 38% of intracerebral hemorrhage
(ICH) patients scanned by computed tomography (CT) within 3 hours of onset. Activated …

Being in the Neurath laboratory gave me an excellent chance to interact with his other
graduate students and postdoctoral fellows. Individuals such as Leon Cunningham gave me …

At present, individual techniques, including intraoperative acute normovolemic
hemodilution, use of tranexamic acid, use of intrathecal morphine, proper positioning, and …

Introduction: Warfarin-associated intracranial hemorrhage (ICH) requires rapid
normalization of clotting function. Current therapies are associated with significant …

Background Abnormalities of the hemostasis can lead to hemorrhage, and on the other
hand to thrombosis. Intracranial neoplasms, complex surgical procedures, and head injury …