Gut microbiota-derived metabolites and cardiovascular disease risk: a systematic review of prospective cohort studies

R Sanchez-Gimenez, W Ahmed-Khodja, Y Molina… - Nutrients, 2022 - mdpi.com
Gut microbiota-derived metabolites have recently attracted considerable attention due to
their role in host-microbial crosstalk and their link with cardiovascular health. The MEDLINE …

Indoxyl sulfate, a uremic endotheliotoxin

G Lano, S Burtey, M Sallée - Toxins, 2020 - mdpi.com
Chronic kidney disease (CKD) is associated with a high prevalence of cardiovascular
diseases. During CKD, the uremic toxin indoxyl sulfate (IS)—derived from tryptophan …

Uraemic solutes as therapeutic targets in CKD-associated cardiovascular disease

JD Ravid, MH Kamel, VC Chitalia - Nature Reviews Nephrology, 2021 - nature.com
Chronic kidney disease (CKD) is characterized by the retention of a myriad of solutes termed
uraemic (or uremic) toxins, which inflict damage to several organs, including the …

The correlation between gut microbiome and atrial fibrillation: pathophysiology and therapeutic perspectives

N Li, L Wang, L Li, MZ Yang, QX Wang, XW Bai… - Military Medical …, 2023 - Springer
Regulation of gut microbiota and its impact on human health is the theme of intensive
research. The incidence and prevalence of atrial fibrillation (AF) are continuously escalating …

Uremic toxins and vascular dysfunction

I Six, N Flissi, G Lenglet, L Louvet, S Kamel, M Gallet… - Toxins, 2020 - mdpi.com
Vascular dysfunction is an essential element found in many cardiovascular pathologies and
in pathologies that have a cardiovascular impact such as chronic kidney disease (CKD) …

[HTML][HTML] Application of a nanotip array-based electrochemical sensing platform for detection of indole derivatives as key indicators of gut microbiota health

X Wang, S Shi, F Zhang, S Li, J Tan, B Su… - Alexandria Engineering …, 2023 - Elsevier
The human gut microbiota plays a vital role in health and disease. Indole derivatives like
indole, tryptamine and indoxyl sulfate represent important microbiota-associated metabolites …

Uremic toxins and cardiovascular risk in chronic kidney disease: what have we learned recently beyond the past findings?

C El Chamieh, S Liabeuf, Z Massy - Toxins, 2022 - mdpi.com
Patients with chronic kidney disease (CKD) have an elevated prevalence of atheromatous
(ATH) and/or non-atheromatous (non-ATH) cardiovascular disease (CVD) due to an array of …

Gut microbiome and cardiovascular disease

Y Zhao, Z Wang - Current opinion in cardiology, 2020 - journals.lww.com
In this review, we discuss the molecular mechanisms of gut microbiome contributing to CVD,
which include gut microbes translocalization to aortic artery because of gut barrier defect to …

The AKI-to-CKD Transition: The Role of Uremic Toxins

C André, S Bodeau, S Kamel, Y Bennis… - International Journal of …, 2023 - mdpi.com
After acute kidney injury (AKI), renal function continues to deteriorate in some patients. In a
pro-inflammatory and profibrotic environment, the proximal tubules are subject to …

The possible role of physical activity in the modulation of gut microbiota in chronic kidney disease and its impact on cardiovascular risk: a narrative review

A Noce, E Tranchita, G Marrone, E Grazioli… - European Review for …, 2023 - art.torvergata.it
Chronic degenerative non-communicable diseases (CDNCDs), in particular chronic kidney
disease, induce gut microbiota (GM) dysbiosis, which, in turn, worsens the progression of …