Nanoemulsion: Concepts, development and applications in drug delivery

Y Singh, JG Meher, K Raval, FA Khan… - Journal of controlled …, 2017 - Elsevier
Nanoemulsions are biphasic dispersion of two immiscible liquids: either water in oil (W/O) or
oil in water (O/W) droplets stabilized by an amphiphilic surfactant. These come across as …

Effect of zeta potential on the properties of nano-drug delivery systems-a review (Part 2)

S Honary, F Zahir - Tropical journal of pharmaceutical research, 2013 - ajol.info
The zeta potential (ZP) of colloidal systems and nano-medicines, as well as their particle
size exert a major effect on the various properties of nano-drug delivery systems. Not only …

Therapeutic nanoemulsions in ophthalmic drug administration: Concept in formulations and characterization techniques for ocular drug delivery

M Singh, S Bharadwaj, KE Lee, SG Kang - Journal of Controlled Release, 2020 - Elsevier
The eye is the specialized part of the body and is comprised of numerous physiological
ocular barriers that limit the drug absorption at the action site. Regardless of various efforts …

Successfully improving ocular drug delivery using the cationic nanoemulsion, novasorb

F Lallemand, P Daull, S Benita… - Journal of drug …, 2012 - Wiley Online Library
Topical ophthalmic delivery of active ingredients can be achieved using cationic
nanoemulsions. In the last decade, Novagali Pharma has successfully developed and …

Recent advances in topical ophthalmic drug delivery with lipid-based nanocarriers

L Gan, J Wang, M Jiang, H Bartlett, D Ouyang… - Drug discovery today, 2013 - Elsevier
Ocular barriers and the poor water solubility of drug candidates present a number of
problems for the development of ocular drug delivery systems. Recently, the emergence of …

Nanotherapy for posterior eye diseases

IP Kaur, S Kakkar - Journal of Controlled Release, 2014 - Elsevier
It is assumed that more than 50% of the most enfeebling ocular diseases have their origin in
the posterior segment. Furthermore, most of these diseases lead to partial or complete …

A review of nanocarrier-mediated drug delivery systems for posterior segment eye disease: Challenges analysis and recent advances

R Wang, Y Gao, A Liu, G Zhai - Journal of drug targeting, 2021 - Taylor & Francis
Posterior segment eye disease is a leading cause of irreversible vision impairment and
blindness. As the unique organ for vision, eyes are protected by various protective barriers …

Trends in formulation approaches for sustained drug delivery to the posterior segment of the eye

A Biswas, AD Choudhury, AC Bisen, S Agrawal… - AAPS …, 2023 - Springer
The eye, an intricate organ comprising physical and physiological barriers, poses a
significant challenge for ophthalmic physicians seeking to treat serious ocular diseases …

Topical delivery of ocular therapeutics: carrier systems and physical methods

JG Souza, K Dias, TA Pereira… - Journal of Pharmacy …, 2014 - academic.oup.com
Objective The basic concepts, major mechanisms, technological developments and
advantages of the topical application of lipid-based systems (microemulsions …

Lipid-based nanocarriers for ophthalmic administration: towards experimental design implementation

FM González-Fernández, A Bianchera, P Gasco… - Pharmaceutics, 2021 - mdpi.com
Nanotherapeutics based on biocompatible lipid matrices allow for enhanced solubility of
poorly soluble compounds in the treatment of ophthalmic diseases, overcoming the …