Overcoming skin barriers through advanced transdermal drug delivery approaches

V Phatale, KK Vaiphei, S Jha, D Patil, M Agrawal… - Journal of controlled …, 2022 - Elsevier
Upon exhaustive research, the transdermal drug delivery system (TDDS) has appeared as a
potential, well-accepted, and popular approach to a novel drug delivery system. Ease of …

Preparation of solid lipid nanoparticles and nanostructured lipid carriers for drug delivery and the effects of preparation parameters of solvent injection method

VA Duong, TTL Nguyen, HJ Maeng - Molecules, 2020 - mdpi.com
Solid lipid nanoparticles (SLNs) and nanostructured lipid carriers (NLCs) have emerged as
potential drug delivery systems for various applications that are produced from …

Lipid-based nanoparticles as a pivotal delivery approach in triple negative breast cancer (TNBC) therapy

A Chaudhuri, DN Kumar, RA Shaik, BG Eid… - International journal of …, 2022 - mdpi.com
Triple-negative breast cancer is considered the most aggressive type of breast cancer
among women and the lack of expressed receptors has made treatment options …

Polymeric micelles: A novel drug delivery system for the treatment of breast cancer

A Chaudhuri, K Ramesh, DN Kumar, D Dehari… - Journal of Drug Delivery …, 2022 - Elsevier
Polymeric micelles have acquired quite an interest as an innovative drug delivery system for
the diagnosis and treatment of breast cancer, as they endeavour numerous benefits over the …

Combination therapy comprising paclitaxel and 5-fluorouracil by using folic acid functionalized bovine milk exosomes improves the therapeutic efficacy against breast …

DN Kumar, A Chaudhuri, D Dehari, A Shekher… - Life, 2022 - mdpi.com
Paclitaxel (PAC) has been approved by FDA for clinical use (Taxol®), yet dose-dependent
severe toxicity due to the adjuvant Cremophor EL® in combination with ethanol is a major …

The latest advances in biomedical applications of chitosan hydrogel as a powerful natural structure with eye-catching biological properties

R Eivazzadeh-Keihan, EB Noruzi, SF Mehrban… - Journal of Materials …, 2022 - Springer
Chitosan is one of the natural cationic polymers with unique properties such as non-toxicity,
biodegradability, biocompatibility, environmentally friendly that has various biomedical …

Dextran methacrylate hydrogel microneedles loaded with doxorubicin and trametinib for continuous transdermal administration of melanoma

S Huang, H Liu, S Huang, T Fu, W Xue, R Guo - Carbohydrate polymers, 2020 - Elsevier
Microneedles (MNs) technology has many advantages and is an ideal local transdermal
drug delivery method. Here we synthesized photocrosslinkable dextran methacrylate …

Antibiofilm potential of silver sulfadiazine-loaded nanoparticle formulations: a study on the effect of DNase-I on microbial biofilm and wound healing activity

KK Patel, DB Surekha, M Tripathi… - Molecular …, 2019 - ACS Publications
Biofilm resistance is one of the severe complications associated with chronic wound
infections, which impose extreme microbial tolerance against antibiotic therapy …

Science of, and insights into, thermodynamic principles for dermal formulations

P Tapfumaneyi, M Imran, SE Alavi, Y Mohammed - Drug Discovery Today, 2023 - Elsevier
Highlights•Thermodynamic principle provides an insight to understand permeation behavior
and the relation between skin and topical product.•Different determinants such as Log P …

Self-assembled lecithin-chitosan nanoparticles improve the oral bioavailability and alter the pharmacokinetics of raloxifene

A Murthy, PR Ravi, H Kathuria, R Vats - International Journal of …, 2020 - Elsevier
In this study, we report the development and evaluation of soy lecithin-chitosan hybrid
nanoparticles to improve the oral bioavailability of raloxifene hydrochloride. The …