The extracellular matrix–the under‐recognized element in lung disease?

JK Burgess, T Mauad, G Tjin, JC Karlsson… - The Journal of …, 2016 - Wiley Online Library
The lung is composed of airways and lung parenchyma, and the extracellular matrix (ECM)
contains the main building blocks of both components. The ECM provides physical support …

The sentinel role of the airway epithelium in asthma pathogenesis

ST Holgate - Immunological reviews, 2011 - Wiley Online Library
The adoption of the concept that asthma is primarily a disease most frequently associated
with elaboration of T‐helper 2 (Th2)‐type inflammation has led to the widely held concept …

Short-term curcuminoid supplementation for chronic pulmonary complications due to sulfur mustard intoxication: positive results of a randomized double-blind placebo …

Y Panahi, M Ghanei, S Bashiri, A Hajihashemi… - Drug …, 2015 - thieme-connect.com
Pulmonary problems are among the most frequent chronic complications of sulfur mustard
(SM) intoxication and are often accompanied by deregulated production of pro-inflammatory …

Biomaterial inks and bioinks for fabricating 3D biomimetic lung tissue: A delicate balancing act between biocompatibility and mechanical printability

L Karamchand, D Makeiff, Y Gao, K Azyat, MJ Serpe… - Bioprinting, 2023 - Elsevier
Three dimensional (3D) bioprinting has rapidly emerged as a major fabrication tool in the
bioengineering of tissue constructs. 3D bioprinting enables the precise deposition of nano …

Airway remodeling in chronic obstructive pulmonary disease and asthma: the role of matrix metalloproteinase-9

K Grzela, M Litwiniuk, W Zagorska, T Grzela - Archivum immunologiae et …, 2016 - Springer
Chronic obstructive pulmonary disease (COPD) and asthma are both associated with airflow
restriction and progressive remodeling, which affect the respiratory tract. Among various …

Hyaluronan and versican in the control of human T-lymphocyte adhesion and migration

SP Evanko, S Potter-Perigo, PL Bollyky, GT Nepom… - Matrix Biology, 2012 - Elsevier
The ability of lymphocytes to migrate freely through connective tissues is vital to efficient
immune function. How the extracellular matrix (ECM) may affect T-cell adhesion and …

Immune induction of airway remodeling

G Guida, AM Riccio - Seminars in immunology, 2019 - Elsevier
Airway remodeling is accepted to be a determining component within the natural history of
asthma. It is a phenomenon characterized by changes in the airways structures that marches …

Understanding fibroblast-immune cell interactions via co-culture models and their role in asthma pathogenesis

F Thiam, SA Yazeedi, K Feng, S Phogat… - Frontiers in …, 2023 - frontiersin.org
Asthma is a chronic lung disease involving airway inflammation and fibrosis. Fibroblasts are
the main effector cells important for lung tissue production which becomes abnormal in …

[HTML][HTML] The three A's in asthma–airway smooth muscle, airway remodeling & angiogenesis

LF Keglowich, P Borger - The open respiratory medicine journal, 2015 - ncbi.nlm.nih.gov
Asthma affects more than 300 million people worldwide and its prevalence is still rising.
Acute asthma attacks are characterized by severe symptoms such as breathlessness …

Prostaglandins in cancer cell adhesion, migration, and invasion

DG Menter, RN DuBois - International journal of cell biology, 2012 - Wiley Online Library
Prostaglandins exert a profound influence over the adhesive, migratory, and invasive
behavior of cells during the development and progression of cancer. Cyclooxygenase‐2 …