The innate immune system is the first line of host defense, and it is capable of resisting both
exogenous pathogenic challenges and endogenous danger signals via different pattern …

Abstract Calcium ions (Ca 2+) act as secondary messengers in a plethora of cellular
processes and play crucial role in cellular organelle function and homeostasis. The average …

Key points This work confirms previous reports that CM4620, a small molecule inhibitor of
Ca2+ entry via store operated Ca2+ entry (SOCE) channels formed by stromal interaction …

Although it has been suggested that toll-like receptor (TLR) 3 and TLR4 activation alters
mesenchymal stromal cells (MSCs)'immunoregulatory function as anti-or pro-inflammatory …

Toll-like receptors (TLRs) are pattern recognition receptors that play a critical role in innate
immune diseases. TLR3, which is localized in the endosomal compartments of …

Background Growing evidence suggests that neuroimmune signaling via Toll‐like receptors
(TLR s) alters brain circuitry related to alcohol use disorders. Both ethanol (EtOH) exposure …

In the last decade, the immunomodulatory properties of mesenchymal stromal cells (MSCs)
have attracted a lot of attention, due to their potential applicability in the treatment of graft …

Abstract Background Disruption of Ca2+ homeostasis after calcium electroporation (CaEP)
in tumors has been shown to elicit an enhanced antitumor effect with varying impacts on …

Calcium release-activated calcium (CRAC) channels are unique among ion channels that
are activated in response to depletion of intracellular calcium stores and are highly …

Spotted fever group rickettsiae are tick-borne obligate intracellular bacteria that infect
microvascular endothelial cells. Humans and mammalian infection results in endothelial cell …