The large Trp gene family encodes transient receptor potential (TRP) proteins that form
novel cation-selective ion channels. In mammals, 28 Trp channel genes have been …

Twenty-five years ago, the first mammalian Transient Receptor Potential Canonical (TRPC)
channel was cloned, opening the vast horizon of the TRPC field. Today, we know that there …

When we edited in 2007 the first issue on transient receptor potential channel in the
Handbook of Experimental Pharmacology, we were all very excited by the progress in this …

In the last decade significant progress has been made in the understanding of
mineralocorticoid receptor (MR) function and its implications for physiology and disease …

Store-operated Ca 2+ entry (SOCE) has emerged as an important mechanism in cardiac
pathology. However, the signals that up-regulate SOCE in the heart remain unexplored …

The first comprehensive single-source reference on the minipig, this accessible manual
provides a resource for research scientists on the potential and use of the minipig as a …

OBJECTIVE Transient receptor potential (TRP) channel–induced cation influx activates
human monocytes, which play an important role in the pathogenesis of atherosclerosis. In …

The role of large-conductance Ca2+-activated K+ (BKCa) channels in regulation of coronary
microvascular function is widely appreciated, but molecular and functional changes …

Metabolic syndrome (MetS) is a collection of risk factors including obesity, dyslipidemia,
insulin resistance/impaired glucose tolerance, and/or hypertension. The incidence of obesity …

Aims Stenting attenuates restenosis, but accelerated coronary artery disease (CAD)
adjacent to the stent (peri-stent CAD) remains a concern in metabolic syndrome (MetS) …