At least 25 bioactive glass (BG) medical devices have been approved for clinical use by
global regulatory agencies. Diverse applications include monolithic implants, bone void …

Lithium (Li) is a metal with critical therapeutic properties ranging from the treatment of
bipolar depression to antibacterial, anticancer, antiviral and pro-regenerative effects. This …

The repair of damaged cartilage still remains a great challenge in clinic. It is demonstrated
that bone marrow stromal cells (BMSCs)‐chondrocytes communication is of great …

Bioactive glass nanoparticles (BGNPs) are of great interest in tissue engineering as they
possess high dissolution rate and capability of being internalized by cells, releasing their …

Bioactive glass has been employed in several medical applications since its inception in
1969. The compositions of these materials have been investigated extensively with …

Objectives Wnt/β-catenin signalling plays important roles in regeneration, particularly in hard
tissues such as bone and teeth, and can be regulated by small molecule antagonists of …

Regeneration of large bone defects remains a clinical challenge until today. While existing
biomaterials are predominantly addressing bone healing via direct, intramembranous …

Bioactive glass nanoparticles (BGNPs) can be internalized by cells, allowing the intracellular
release of dissolution products with therapeutic benefit. Different therapeutic ions can be …

Canonical Wnt signaling regulation is essential for controlling stemness and differentiation
of mesenchymal stem cells (MSCs). However, the mechanism through which canonical Wnt …

The repair of articular cartilage lesions in weight-bearing joints remains as a significant
challenge due to the low regenerative capacity of this tissue. Hydrogels are candidates to …