Leptin action in normal and pathological pregnancies

A Pérez‐Pérez, A Toro… - Journal of cellular …, 2018 - Wiley Online Library
Leptin is now considered an important signalling molecule of the reproductive system, as it
regulates the production of gonadotrophins, the blastocyst formation and implantation, the …

The role of the adipokines in the most common gestational complications

P Gutaj, R Sibiak, M Jankowski, K Awdi, R Bryl… - International journal of …, 2020 - mdpi.com
Adipocytokines are hormonally active molecules that are believed to play a key role in the
regulation of crucial biological processes in the human body. Numerous experimental …

Genetic and epigenetic variations associated with idiopathic recurrent pregnancy loss

LA Arias-Sosa, ID Acosta, E Lucena-Quevedo… - Journal of assisted …, 2018 - Springer
Recurrent pregnancy loss (RPL) is a reproductive disorder defined as two or more
successive and spontaneous pregnancy losses (before 20 weeks of gestation), which affects …

Expression of nutrient transporters in placentas affected by gestational diabetes: role of leptin

P Guadix, I Corrales, T Vilariño-García… - Frontiers in …, 2023 - frontiersin.org
Gestational diabetes mellitus (GDM) is the most frequent pathophysiological state of
pregnancy, which in many cases produces fetuses with macrosomia, requiring increased …

Understanding recurrent pregnancy loss: recent advances on its etiology, clinical diagnosis, and management

C Cao, S Bai, J Zhang, X Sun, A Meng, H Chen - Medical Review, 2023 - degruyter.com
Recurrent pregnancy loss (RPL) has become an important reproductive health issue
worldwide. RPL affects about 2%–3% of reproductive-aged women, and makes serious …

Obesity and recurrent miscarriage: The interconnections between adipose tissue and the immune system

CCRA Gonçalves, BM Feitosa… - American Journal of …, 2023 - Wiley Online Library
Currently, obesity is considered a global public health problem. It is the main risk factor for
noncommunicable diseases and reproductive complications, such as recurrent miscarriage …

Maternal candidate gene variants, epigenetic factors, and susceptibility to idiopathic recurrent pregnancy loss: A systematic review

M Kaur, R Kaur, K Chhabra… - International Journal of …, 2023 - Wiley Online Library
Background Recurrent pregnancy loss is defined as the loss of two or more pregnancies
and is a distressing condition for couples. Objective To investigate the relationship between …

TLR signaling pathway and the effects of main immune cells and epigenetics factors on the diagnosis and treatment of infertility and sterility

K Babaei, MA Nezhad, SNS Ziabari, E Mirzajani… - Heliyon, 2024 - cell.com
Recurrent pregnancy loss (RPL), often known as spontaneous miscarriages occurring two or
more times in a row, is a reproductive disease that affects certain couples. The cause of RPL …

Association between interleukin-32 and interleukin-17A single nucleotide polymorphisms and serum levels with polycystic ovary syndrome

F Hesampour, BN Jahromi, F Tahmasebi… - Iranian Journal of …, 2019 - ijaai.tums.ac.ir
Polycystic ovary syndrome (PCOS) is correlated with low-grade chronic inflammation.
Interleukin-17A (IL-17A) and Interleukin-32 (IL-32) are two members of the pro-inflammatory …

Immunogenetic Role of IL17A polymorphism in the pathogenesis of recurrent miscarriage

S Ali, S Majid, MN Ali, MZ Banday, S Taing… - Journal of Clinical …, 2022 - mdpi.com
Interleukin-17A (IL17A) is a proinflammatory cytokine and is assumed to play an important
role in fetal rejection. In order to evaluate the potential role of IL17A polymorphism in the …