Osteoarthritis is a complex degenerative disease that affects the entire joint tissue. Currently,
non-surgical treatments for osteoarthritis focus on relieving pain. While end-stage …

Gap junction intercellular communication (GJIC) allows the transfer of material, message
and energy between cells, which influences cell behaviors including cell proliferation …

Objectives Significant advances have been made in our understanding of osteoarthritis (OA)
pathogenesis; however, no disease-modifying therapies have been identified. This review …

Gene doping, an activity which abuses and misuses gene therapy, is a major concern in
sports and horseracing industries. Effective methods capable of detecting and monitoring …

Objective To explore how systemic factors that modify knee osteoarthritis risk are connected
to 'whole-joint'structural changes by evaluating the effects of high-fat diet and wheel running …

Background: Despite several studies on the effect of adeno-associated virus (AAV)-based
therapeutics on osteoarthritis (OA), information on the transduction efficiency and applicable …

The misuse of genetic manipulation technology to enhance athletic performance is termed
gene doping which is prohibited in human sports, horseracing, and equestrian sports …

Equine recurrent uveitis (ERU) is a spontaneous, painful, and vision threatening disease
affecting up to 25% of equine populations worldwide. Current treatments of ERU are non …

Illicit administration of transgene into horses is a form of gene doping that has been a key
concern in equine sports. The large number of potential performance‐enhancing transgenes …

The concern about gene doping has remained high in horseracing and other equestrian
competitions. Our laboratory has previously developed a duplex quantitative polymerase …