Discovery of repurposing drug candidates for the treatment of diseases caused by pathogenic free-living amoebae

CA Rice, BL Colon, E Chen, MV Hull… - PLoS Neglected …, 2020 - journals.plos.org
Diseases caused by pathogenic free-living amoebae include primary amoebic
meningoencephalitis (Naegleria fowleri), granulomatous amoebic encephalitis …

Discovery of anti-amoebic inhibitors from screening the MMV pandemic response box on Balamuthia mandrillaris, Naegleria fowleri, and Acanthamoeba castellanii

CA Rice, EV Troth, AC Russell, DE Kyle - Pathogens, 2020 - mdpi.com
Pathogenic free-living amoebae, Balamuthia mandrillaris, Naegleria fowleri, and several
Acanthamoeba species are the etiological agents of severe brain diseases, with case …

Phenotypic screens reveal posaconazole as a rapidly acting amebicidal combination partner for treatment of primary amoebic meningoencephalitis

BL Colon, CA Rice, RK Guy… - The Journal of Infectious …, 2019 - academic.oup.com
Naegleria fowleri is the causative agent of primary amoebic meningoencephalitis (PAM),
which is fatal in> 97% of cases. In this study, we aimed to identify new, rapidly acting drugs …

Sub-Genotyping of Acanthamoeba T4 Complex: Experience from North India

K Megha, M Sharma, A Gupta, R Sehgal, S Khurana - Parasitologia, 2023 - mdpi.com
The Acanthamoeba genus comprises the free-living amoebae that are ubiquitously present
as opportunistic pathogens. They cause serious human diseases—for instance …

Biochemical profile, liver and kidney selenium (Se) status during acanthamoebiasis in a mouse model

N Łanocha-Arendarczyk… - Folia Biologica …, 2018 - ingentaconnect.com
The aim of the present study was to determine biochemical parameters and Se
concentrations in the main detoxication organs in immunocompetent and …

Protein profiling of Acanthamoeba species using MALDI-TOF MS for specific identification of Acanthamoeba genotype

K Megha, M Sharma, A Gupta, R Sehgal… - Parasitology research, 2018 - Springer
Acanthamoeba spp. are ubiquitous in the environment and have the potential to cause
severe infections. The different genotypes of Acanthamoeba have been shown to influence …

Metagenomic next-generation sequencing-assisted diagnosis of a rare case of primary cutaneous acanthamoebiasis in an HIV patient: a case report

W Fan, P Li, Q Wei, X Liu, Y Cai, B Li… - Frontiers in Cellular and …, 2024 - frontiersin.org
Pathogenic and free-living Acanthamoeba are widely distributed in the environment and
have been reported to cause keratitis and universally fatal encephalitis. Primary cutaneous …

[PDF][PDF] Wpływ pełzaków z rodzaju Acanthamoeba na procesy zapalne zachodzące w organizmie żywiciela

K Kot - 2021 - ppm.pum.edu.pl
BAL popłuczyny oskrzelowo-pęcherzykowe C1 białko dopełniacza C1 C1q białko
dopełniacza C1q C3b białko dopełniacza C3b, opsonina CA skórna akantameboza CAT …