Bile acids are important hydroxylated steroids that are synthesized in the liver from
cholesterol for intestinal absorption of lipids and other fatty-nutrient. They also display …

Cholangiocarcinomas (CCAs) are a heterogeneus group of malignant tumors that originate
from the biliary tract. They are usually diagnosed in advanced stages, leading to a dismal …

Pancreatic cancer (PC) is one of the most aggressive malignancies with high mortality due
to a complex and latent pathogenesis leading to the severe lack of early diagnosis methods …

In intensive aquaculture systems, dissolved oxygen (DO) is the most critical and limiting
factor for the development and health of aquatic organisms. Hypoxia is a common …

Bile acid-modified nanomedicine is a promising strategy to improve oral bioavailability.
However, the efficiencies of different bile acids have not been clarified. To clarify this issue …

Bile acids (BAs) are currently considered as causative agents for Cholangiocarcinoma
(CCA). However, the profile of circulating BAs in CCA have not been well characterized. The …

Background: The present study aimed to assess the ability of serum bile acid profiles to
predict the development of nonalcoholic fatty liver (NAFL) in type 2 diabetes mellitus (T2DM) …

Objectives The aim of this study was to evaluate effect of Lactobacillus plantarum HT121 on
serum lipid profile, gut microbiota, and liver transcriptome and metabolomics. Methods L …

In the past ten years, our understanding of the importance of bile acids has expanded from
fat absorption and glucose/lipid/energy homeostasis into potential therapeutic targets for …

Biliary tract neoplasms, which originate from the intrahepatic or extrahepatic biliary
epithelium, are relatively rare but diagnostically challenging types of tumours, and their …